Two new sesquiterpenoids from endophytic fungus J3 isolated from Mangrove Plant Ceriops tagal

Two new sesquiterpenoids, named 2 α -hydroxyxylaranol B ( 1 ) and 4 β -hydroxyxylaranol B ( 2 ), together with a known diterpenoid 3,4-seco-sonderianol ( 3 ) were isolated from the fermentation of endophytic fungus J3 of Ceriops tagal . Their structures were elucidated based on spectroscopic methods...

Full description

Saved in:
Bibliographic Details
Published in:Archives of pharmacal research 2015, 38(5), , pp.673-676
Main Authors: Zeng, Yan-Bo, Gu, Hai-Gang, Zuo, Wen-Jian, Zhang, Li-Li, Bai, Hong-Jin, Guo, Zhi-Kai, Proksch, Peter, Mei, Wen-Li, Dai, Hao-Fu
Format: Article
Language:English
Subjects:
Cytotoxins - chemistry
Cytotoxins - isolation & purification
Endophytes - isolation & purification
Fungi - isolation & purification
Humans
K562 Cells
Medicine
Pharmacology/Toxicology
Pharmacy
Plant Leaves
Research Article
Rhizophoraceae
Sesquiterpenes - chemistry
Sesquiterpenes - isolation & purification
약학
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Two new sesquiterpenoids, named 2 α -hydroxyxylaranol B ( 1 ) and 4 β -hydroxyxylaranol B ( 2 ), together with a known diterpenoid 3,4-seco-sonderianol ( 3 ) were isolated from the fermentation of endophytic fungus J3 of Ceriops tagal . Their structures were elucidated based on spectroscopic methods including 1D and 2D NMR (HMQC, 1 H- 1 H COSY and HMBC). All compounds were evaluated for their cytotoxic activities by MTT method, and compound 3 exhibited cytotoxic activities against K562, SGC-7901, and BEL-7402 cell lines.
ISSN:0253-6269
1976-3786
DOI:10.1007/s12272-014-0448-8