Application of magnetic nanoparticle for controlled tissue assembly and tissue engineering

Magnetic nanoparticles have been subjected to extensive studies in the past few decades owing to their promising potentials in biomedical applications. The versatile intrinsic properties of magnetic nanoparticles enable their use in many biomedical applications. Recently, magnetic nanoparticles were...

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Bibliographic Details
Published in:Archives of pharmacal research 2014, 37(1), , pp.120-128
Main Authors: Lee, Eunjee A., Yim, Hyungu, Heo, Jiseung, Kim, Hwan, Jung, Giyoung, Hwang, Nathaniel S.
Format: Article
Language:English
Subjects:
Animals
Cell Culture Techniques
Cell Differentiation
Cell Movement
Cells, Cultured
Humans
Magnetics - methods
Magnetite Nanoparticles
Medicine
Nanomedicine - methods
Organogenesis
Pharmacology/Toxicology
Pharmacy
Phenotype
Regenerative Medicine - methods
Review
Tissue Engineering - methods
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Summary:Magnetic nanoparticles have been subjected to extensive studies in the past few decades owing to their promising potentials in biomedical applications. The versatile intrinsic properties of magnetic nanoparticles enable their use in many biomedical applications. Recently, magnetic nanoparticles were utilized to control the cell’s function. In addition, intracellular delivery of magnetic nanoparticles allowed cell’s positioning by appropriate use of magnetic field and created cellular cluster. Furthermore, magnetic nanoparticles have been utilized to assemble more complex tissue structures than those that are achieved by conventional scaffold-based tissue engineering strategies. This review addresses recent work in the use magnetic nanoparticle for controlled tissue assembly and complex tissue formation.
ISSN:0253-6269
1976-3786
DOI:10.1007/s12272-013-0303-3