Antioxidative compounds from Quercus salicina Blume Stem

The chromatographic separation of MeOH extract from the Quercus salicina Blume Stem led to the isolation of five phenolic compounds. Using spectroscopic methods, the structures of these compounds were determined as D-threo-guaiacylglycerol 8- O - β -D-(6′- O -galloyl)glucopyranoside (1), 9-methoxy-D...

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Bibliographic Details
Published in:Archives of pharmacal research 2008, 31(3), , pp.274-278
Main Authors: Kim, Jung-il, Kim, Ho-hyun, Kim, Sungun, Lee, Kyoung-tae, Ham, In-hye, Whang, Wan-Kyunn
Format: Article
Language:English
Subjects:
Antioxidants - chemistry
Antioxidants - isolation & purification
Antioxidants - pharmacology
Biphenyl Compounds
Chromatography
Free Radical Scavengers - chemistry
Free Radical Scavengers - isolation & purification
Free Radical Scavengers - pharmacology
Gallic Acid - analogs & derivatives
Gallic Acid - pharmacology
Glucosides - pharmacology
Glycerol - analogs & derivatives
Glycerol - pharmacology
Humans
Lipid Peroxidation - drug effects
Lipoproteins, LDL - metabolism
Magnetic Resonance Spectroscopy
Medicine
Pharmacology/Toxicology
Pharmacy
Picrates - chemistry
Plant Stems
Quercetin - pharmacology
Quercus - chemistry
Thiobarbituric Acid Reactive Substances - metabolism
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Summary:The chromatographic separation of MeOH extract from the Quercus salicina Blume Stem led to the isolation of five phenolic compounds. Using spectroscopic methods, the structures of these compounds were determined as D-threo-guaiacylglycerol 8- O - β -D-(6′- O -galloyl)glucopyranoside (1), 9-methoxy-D-threo-guaiacylglycerol 8- O - β -D-(6′- O -galloyl)glucopyranoside (2), 6″- O -galloyl salidroside (3), methyl gallate (4), quercetin (5). We measured radical scavenging activity with the DPPH method and the anti-lipid peroxidative efficacy on human LDL with TBARS assay, with the result that all these compounds exhibited the antioxidative activity.
ISSN:0253-6269
1976-3786
DOI:10.1007/s12272-001-1152-2