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Chemical constituents of Acanthus ilicifolius L. and effect on osteoblastic MC3T3E1 cells
A new coumaric acid derivative called acancifoliuside ( 1 ) and six known compounds as acteoside ( 2 ), isoacteoside ( 3 ), acanthaminoside ( 4 ), (+)-lyoniresinol 3a- O -β-glucopyranoside ( 5 ), (−)-lyoniresinol ( 6 ), and α-amyrin ( 7 ), were isolated from the methanolic extract of the leaves of A...
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| Published in: | Archives of pharmacal research 2008, 31(7), , pp.823-829 |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Article |
| Language: | English |
| Subjects: | |
| Citations: | Items that this one cites Items that cite this one |
| Online Access: | Get full text |
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| Summary: | A new coumaric acid derivative called acancifoliuside (
1
) and six known compounds as acteoside (
2
), isoacteoside (
3
), acanthaminoside (
4
), (+)-lyoniresinol 3a-
O
-β-glucopyranoside (
5
), (−)-lyoniresinol (
6
), and α-amyrin (
7
), were isolated from the methanolic extract of the leaves of
Acanthus ilicifolius
L. (Acanthaceae). Their structures were determined by spectroscopic methods and a comparison with the spectral data reported in the literature. The effects of the compounds on the function of osteoblastic MC3T3-E1 cells were tested. Compounds
2, 3
, and
5
(30 μM) increased the growth and differentiation of osteoblasts significantly (
P |
|---|---|
| ISSN: | 0253-6269 1976-3786 |
| DOI: | 10.1007/s12272-001-1232-3 |