Application of Coupling Reaction between Lithiated Toluamideand Benzonitrile for the Synthesis of Phenolic Benzo[c]phenanthridineAlkaloid, Oxyterihanine

The total synthesis of the natural phenolic benzo[c]phenanthridine alkaloid, oxyterihanine, was accomplished via substituted 3-arylisoquinoline intermediate. The key reaction was a coupling between the o-toluamide 4 and the benzonitrile 5. KCI Citation Count: 9

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Bibliographic Details
Published in:Archives of pharmacal research 2008, 31(1), , pp.6-9
Main Authors: Thanh Nguyen Le, Hue Thi My Van, Suh-Hee Lee, 최현진, 이광열, 강복윤, 조원제
Format: Article
Language:English
Subjects:
약학
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Summary:The total synthesis of the natural phenolic benzo[c]phenanthridine alkaloid, oxyterihanine, was accomplished via substituted 3-arylisoquinoline intermediate. The key reaction was a coupling between the o-toluamide 4 and the benzonitrile 5. KCI Citation Count: 9
ISSN:0253-6269
1976-3786