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Diagnostic Criteria on 18F-FDG PET/CT for Differentiating Benign from Malignant Focal Hypermetabolic Lesions of Parotid Gland

Purpose We investigated PET/CT diagnostic criteria for differentiating benign from malignant parotid lesions with focal 18 F-FDG uptake. Methods The subjects of the study were 272 patients who exhibited focal 18 F-FDG uptake of the parotid gland. Sixty-eight pathologically confirmed parotid lesions...

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Published in:Nuclear medicine and molecular imaging 2012, 46(2), , pp.95-101
Main Authors: Park, Soo Bin, Choi, Joon Young, Lee, Eun Jeong, Yoo, Jang, Cheon, Miju, Cho, Suk Kyong, Choe, Yearn Seong, Lee, Kyung-Han, Kim, Byung-Tae
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Language:English
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Summary:Purpose We investigated PET/CT diagnostic criteria for differentiating benign from malignant parotid lesions with focal 18 F-FDG uptake. Methods The subjects of the study were 272 patients who exhibited focal 18 F-FDG uptake of the parotid gland. Sixty-eight pathologically confirmed parotid lesions from 67 patients were included. The maximum SUV (SUVmax), uptake patterns (homogeneous vs. heterogeneous), size measured by CT, maximum Hounsfield units (HUmax) and margins on CT (well vs. ill defined) of each parotid lesion on PET/CT images were compared with final diagnoses. Results Thirty-two parotid lesions were histologically proven to be malignant. There were significant differences in uptake patterns (cancer incidence, heterogeneous:homogeneous = 79.2%:29.5%, p 
ISSN:1869-3474
1869-3482
DOI:10.1007/s13139-012-0135-y