Anti-adipogenic effects in 3T3-L1 cells of acetone extracts and fractions from Styrax japonica fruit

Reduction in reactive oxygen species (ROS) production facilitated by Styrax japonica (SJ) extracts and fractions for inhibition of obesity development through inhibition of adipogenesis was investigated. Treatment of cells with SJ extracts and fractions did not result in changes in cell viability. S...

Full description

Saved in:
Bibliographic Details
Published in:Food science and biotechnology 2015, 24(4), , pp.1513-1521
Main Authors: Kim, Jin Kyu, Nam, Hajin, Kim, Yoo Yeon, Jung, Harry, Choi, Yoon Soo, Oh, Joa Sub, Chun, Su Kyoung, Suh, Jun Gyo
Format: Article
Language:English
Subjects:
Chemistry
Chemistry and Materials Science
Food Science
Nutrition
Research Article
Styrax
식품과학
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-c354t-4739b4898f84f20fe8882a85fca4607a91157335e8220836c5e1aeb1779ff0113
cites cdi_FETCH-LOGICAL-c354t-4739b4898f84f20fe8882a85fca4607a91157335e8220836c5e1aeb1779ff0113
container_end_page 1521
container_issue 4
container_start_page 1513
container_title Food science and biotechnology
container_volume 24
creator Kim, Jin Kyu
Nam, Hajin
Kim, Yoo Yeon
Jung, Harry
Choi, Yoon Soo
Oh, Joa Sub
Chun, Su Kyoung
Suh, Jun Gyo
description Reduction in reactive oxygen species (ROS) production facilitated by Styrax japonica (SJ) extracts and fractions for inhibition of obesity development through inhibition of adipogenesis was investigated. Treatment of cells with SJ extracts and fractions did not result in changes in cell viability. SJ extracts and fractions inhibited lipid accumulation in a dose-dependent manner during adipogenesis. Expressions of PPARγ and C/EBPα, key adipogenic markers, were decreased in cells treated with SJ extracts and fractions. Inhibitory effects of SJ extracts and fractions were the most powerful in the early stages of differentiation (days 0-2). Intracellular ROS production was decreased in cells treated with SJ extracts and fractions. SJ extracts and fractions can inhibit adipogenesis via reduced ROS levels, which involves down-regulation of adipogenic transcription factors.
doi_str_mv 10.1007/s10068-015-0195-8
format article
fullrecord <record><control><sourceid>proquest_nrf_k</sourceid><recordid>TN_cdi_nrf_kci_oai_kci_go_kr_ARTI_122783</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1712575592</sourcerecordid><originalsourceid>FETCH-LOGICAL-c354t-4739b4898f84f20fe8882a85fca4607a91157335e8220836c5e1aeb1779ff0113</originalsourceid><addsrcrecordid>eNp9kMtKAzEUhoMoWKsP4C5LN9FcJpPMshRvUBC0rkOaJiW9JGMyA-3bm3EEdy6Sczh8_4HzAXBL8D3BWDzk8tcSYcLLaziSZ2BCcUNRXfH6HEwIpTUSAstLcJXztsCEimoC1rPQeaTXvo0bG7yB1jlrugx9gGzJ0IJAY_f7DKOD2tguBgvtsUt6YHRYQze0PoZcuniAH90p6SPc6jaWbboMe99dgwun99ne_NYp-Hx6XM5f0OLt-XU-WyDDeNWhSrBmVclGOlk5ip2VUlItuTO6qrHQDSFcMMatpBRLVhtuibYrIkTjHCaETcHduDckp3bGq6j9T91EtUtq9r58VUWEkOwPbVP86m3u1MHn4VIdbOyzIoJQLjhvaEHJiJoUc07WqTb5g04nRbAa5KtRviry1SBfyZKhYyYXNmxsUtvYp1CO_yf0DQA1hXs</addsrcrecordid><sourcetype>Open Website</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1712575592</pqid></control><display><type>article</type><title>Anti-adipogenic effects in 3T3-L1 cells of acetone extracts and fractions from Styrax japonica fruit</title><source>Springer Link</source><creator>Kim, Jin Kyu ; Nam, Hajin ; Kim, Yoo Yeon ; Jung, Harry ; Choi, Yoon Soo ; Oh, Joa Sub ; Chun, Su Kyoung ; Suh, Jun Gyo</creator><creatorcontrib>Kim, Jin Kyu ; Nam, Hajin ; Kim, Yoo Yeon ; Jung, Harry ; Choi, Yoon Soo ; Oh, Joa Sub ; Chun, Su Kyoung ; Suh, Jun Gyo</creatorcontrib><description>Reduction in reactive oxygen species (ROS) production facilitated by Styrax japonica (SJ) extracts and fractions for inhibition of obesity development through inhibition of adipogenesis was investigated. Treatment of cells with SJ extracts and fractions did not result in changes in cell viability. SJ extracts and fractions inhibited lipid accumulation in a dose-dependent manner during adipogenesis. Expressions of PPARγ and C/EBPα, key adipogenic markers, were decreased in cells treated with SJ extracts and fractions. Inhibitory effects of SJ extracts and fractions were the most powerful in the early stages of differentiation (days 0-2). Intracellular ROS production was decreased in cells treated with SJ extracts and fractions. SJ extracts and fractions can inhibit adipogenesis via reduced ROS levels, which involves down-regulation of adipogenic transcription factors.</description><identifier>ISSN: 1226-7708</identifier><identifier>EISSN: 2092-6456</identifier><identifier>DOI: 10.1007/s10068-015-0195-8</identifier><language>eng</language><publisher>Seoul: The Korean Society of Food Science and Technology</publisher><subject>Chemistry ; Chemistry and Materials Science ; Food Science ; Nutrition ; Research Article ; Styrax ; 식품과학</subject><ispartof>Food Science and Biotechnology, 2015, 24(4), , pp.1513-1521</ispartof><rights>The Korean Society of Food Science and Technology and Springer Science+Business Media Dordrecht 2015</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c354t-4739b4898f84f20fe8882a85fca4607a91157335e8220836c5e1aeb1779ff0113</citedby><cites>FETCH-LOGICAL-c354t-4739b4898f84f20fe8882a85fca4607a91157335e8220836c5e1aeb1779ff0113</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.kci.go.kr/kciportal/ci/sereArticleSearch/ciSereArtiView.kci?sereArticleSearchBean.artiId=ART002019827$$DAccess content in National Research Foundation of Korea (NRF)$$Hfree_for_read</backlink></links><search><creatorcontrib>Kim, Jin Kyu</creatorcontrib><creatorcontrib>Nam, Hajin</creatorcontrib><creatorcontrib>Kim, Yoo Yeon</creatorcontrib><creatorcontrib>Jung, Harry</creatorcontrib><creatorcontrib>Choi, Yoon Soo</creatorcontrib><creatorcontrib>Oh, Joa Sub</creatorcontrib><creatorcontrib>Chun, Su Kyoung</creatorcontrib><creatorcontrib>Suh, Jun Gyo</creatorcontrib><title>Anti-adipogenic effects in 3T3-L1 cells of acetone extracts and fractions from Styrax japonica fruit</title><title>Food science and biotechnology</title><addtitle>Food Sci Biotechnol</addtitle><description>Reduction in reactive oxygen species (ROS) production facilitated by Styrax japonica (SJ) extracts and fractions for inhibition of obesity development through inhibition of adipogenesis was investigated. Treatment of cells with SJ extracts and fractions did not result in changes in cell viability. SJ extracts and fractions inhibited lipid accumulation in a dose-dependent manner during adipogenesis. Expressions of PPARγ and C/EBPα, key adipogenic markers, were decreased in cells treated with SJ extracts and fractions. Inhibitory effects of SJ extracts and fractions were the most powerful in the early stages of differentiation (days 0-2). Intracellular ROS production was decreased in cells treated with SJ extracts and fractions. SJ extracts and fractions can inhibit adipogenesis via reduced ROS levels, which involves down-regulation of adipogenic transcription factors.</description><subject>Chemistry</subject><subject>Chemistry and Materials Science</subject><subject>Food Science</subject><subject>Nutrition</subject><subject>Research Article</subject><subject>Styrax</subject><subject>식품과학</subject><issn>1226-7708</issn><issn>2092-6456</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><recordid>eNp9kMtKAzEUhoMoWKsP4C5LN9FcJpPMshRvUBC0rkOaJiW9JGMyA-3bm3EEdy6Sczh8_4HzAXBL8D3BWDzk8tcSYcLLaziSZ2BCcUNRXfH6HEwIpTUSAstLcJXztsCEimoC1rPQeaTXvo0bG7yB1jlrugx9gGzJ0IJAY_f7DKOD2tguBgvtsUt6YHRYQze0PoZcuniAH90p6SPc6jaWbboMe99dgwun99ne_NYp-Hx6XM5f0OLt-XU-WyDDeNWhSrBmVclGOlk5ip2VUlItuTO6qrHQDSFcMMatpBRLVhtuibYrIkTjHCaETcHduDckp3bGq6j9T91EtUtq9r58VUWEkOwPbVP86m3u1MHn4VIdbOyzIoJQLjhvaEHJiJoUc07WqTb5g04nRbAa5KtRviry1SBfyZKhYyYXNmxsUtvYp1CO_yf0DQA1hXs</recordid><startdate>20150801</startdate><enddate>20150801</enddate><creator>Kim, Jin Kyu</creator><creator>Nam, Hajin</creator><creator>Kim, Yoo Yeon</creator><creator>Jung, Harry</creator><creator>Choi, Yoon Soo</creator><creator>Oh, Joa Sub</creator><creator>Chun, Su Kyoung</creator><creator>Suh, Jun Gyo</creator><general>The Korean Society of Food Science and Technology</general><general>한국식품과학회</general><scope>AAYXX</scope><scope>CITATION</scope><scope>7QO</scope><scope>8FD</scope><scope>FR3</scope><scope>P64</scope><scope>ACYCR</scope></search><sort><creationdate>20150801</creationdate><title>Anti-adipogenic effects in 3T3-L1 cells of acetone extracts and fractions from Styrax japonica fruit</title><author>Kim, Jin Kyu ; Nam, Hajin ; Kim, Yoo Yeon ; Jung, Harry ; Choi, Yoon Soo ; Oh, Joa Sub ; Chun, Su Kyoung ; Suh, Jun Gyo</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c354t-4739b4898f84f20fe8882a85fca4607a91157335e8220836c5e1aeb1779ff0113</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Chemistry</topic><topic>Chemistry and Materials Science</topic><topic>Food Science</topic><topic>Nutrition</topic><topic>Research Article</topic><topic>Styrax</topic><topic>식품과학</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kim, Jin Kyu</creatorcontrib><creatorcontrib>Nam, Hajin</creatorcontrib><creatorcontrib>Kim, Yoo Yeon</creatorcontrib><creatorcontrib>Jung, Harry</creatorcontrib><creatorcontrib>Choi, Yoon Soo</creatorcontrib><creatorcontrib>Oh, Joa Sub</creatorcontrib><creatorcontrib>Chun, Su Kyoung</creatorcontrib><creatorcontrib>Suh, Jun Gyo</creatorcontrib><collection>CrossRef</collection><collection>Biotechnology Research Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Korean Citation Index</collection><jtitle>Food science and biotechnology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kim, Jin Kyu</au><au>Nam, Hajin</au><au>Kim, Yoo Yeon</au><au>Jung, Harry</au><au>Choi, Yoon Soo</au><au>Oh, Joa Sub</au><au>Chun, Su Kyoung</au><au>Suh, Jun Gyo</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Anti-adipogenic effects in 3T3-L1 cells of acetone extracts and fractions from Styrax japonica fruit</atitle><jtitle>Food science and biotechnology</jtitle><stitle>Food Sci Biotechnol</stitle><date>2015-08-01</date><risdate>2015</risdate><volume>24</volume><issue>4</issue><spage>1513</spage><epage>1521</epage><pages>1513-1521</pages><issn>1226-7708</issn><eissn>2092-6456</eissn><abstract>Reduction in reactive oxygen species (ROS) production facilitated by Styrax japonica (SJ) extracts and fractions for inhibition of obesity development through inhibition of adipogenesis was investigated. Treatment of cells with SJ extracts and fractions did not result in changes in cell viability. SJ extracts and fractions inhibited lipid accumulation in a dose-dependent manner during adipogenesis. Expressions of PPARγ and C/EBPα, key adipogenic markers, were decreased in cells treated with SJ extracts and fractions. Inhibitory effects of SJ extracts and fractions were the most powerful in the early stages of differentiation (days 0-2). Intracellular ROS production was decreased in cells treated with SJ extracts and fractions. SJ extracts and fractions can inhibit adipogenesis via reduced ROS levels, which involves down-regulation of adipogenic transcription factors.</abstract><cop>Seoul</cop><pub>The Korean Society of Food Science and Technology</pub><doi>10.1007/s10068-015-0195-8</doi><tpages>9</tpages></addata></record>
fulltext fulltext
identifier ISSN: 1226-7708
ispartof Food Science and Biotechnology, 2015, 24(4), , pp.1513-1521
issn 1226-7708
2092-6456
language eng
recordid cdi_nrf_kci_oai_kci_go_kr_ARTI_122783
source Springer Link
subjects Chemistry
Chemistry and Materials Science
Food Science
Nutrition
Research Article
Styrax
식품과학
title Anti-adipogenic effects in 3T3-L1 cells of acetone extracts and fractions from Styrax japonica fruit
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-03T19%3A05%3A51IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_nrf_k&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Anti-adipogenic%20effects%20in%203T3-L1%20cells%20of%20acetone%20extracts%20and%20fractions%20from%20Styrax%20japonica%20fruit&rft.jtitle=Food%20science%20and%20biotechnology&rft.au=Kim,%20Jin%20Kyu&rft.date=2015-08-01&rft.volume=24&rft.issue=4&rft.spage=1513&rft.epage=1521&rft.pages=1513-1521&rft.issn=1226-7708&rft.eissn=2092-6456&rft_id=info:doi/10.1007/s10068-015-0195-8&rft_dat=%3Cproquest_nrf_k%3E1712575592%3C/proquest_nrf_k%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c354t-4739b4898f84f20fe8882a85fca4607a91157335e8220836c5e1aeb1779ff0113%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=1712575592&rft_id=info:pmid/&rfr_iscdi=true