Radical scavenging and anti-acetylcholinesterase activities of aqueous extract of wild pistachio (Pistacia atlantica Desf.) leaves

• Published in: Food science and biotechnology 2013, 22(2), , pp.515-522
• Main Authors: Peksel, Aysegul, Arisan, Inci, Yanardag, Refiye
• Format: Article
• Language: English
• Subjects: Acetylcholinesterase; Chemistry; Chemistry and Materials Science; Food Science; Nutrition; Pistacia; Research Article; 식품과학
• ISSN: 1226-7708; 2092-6456
• DOI: 10.1007/s10068-013-0109-6

The purpose of this work is to assess the radical scavenging activity, acetylcholinesterase inhibition, and proline content of an aqueous extract from wild pistachio ( Pistacia atlantica Desf.) leaves. The effect of aqueous extract on superoxide radical scavenging, hydroxyl radical scavenging, N,N -dimethyl-1,4-phenylendiammoniumdichloride (DMPD ·+ ) radical scavenging, ABTS ·+ radical scavenging, nitric oxide scavenging, and β-carotene bleaching activities was examined. This study found that the aqueous extract possesses considerable amounts of flavonoids (33.52±2.04 μg catechin equivalents/mg of extract). The effect of this extract in scavenging activity of hydroxyl radical and DMPD ·+ was significantly better than that of ascorbic acid and butylated hydroxyanisole (BHA). The effect of the extract in superoxide and ABTS ·+ was significantly similar than that of tested standard antioxidants. The proline content of the extract was found to be 0.54±0.01 μg proline/mg of extract. Aqueous extract of P. atlantica inhibited acetylcholinesterase activity effectively with IC 50 value of 58.05±0.12 μg/mL.