Effect of Far Infrared Drying on Antioxidant Property, Anti-inflammatory Activity, and Inhibitory Activity in A549 Cells of Gamguk (Chrysanthemum indicum L.) Flower

This research demonstrated and compared the effects of shade and far infrared drying (FIRD) of gamguk (Chrysanthemum indicum L., CE) flowers extract on total phenolic (TP), total flavonoid (TF) content, anticancer and anti-inflammatory activities. The research data revealed that the TP and TF conten...

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Bibliographic Details
Published in:Food science and biotechnology 2012, 21(1), , pp.261-265
Main Authors: Kim, W.W., Kangwon National University, Chuncheon, Republic of Korea, Ghimeray, Amal Kumar, Kangwon National University, Chuncheon, Republic of Korea, Wu, J.C., Kangwon National University, Chuncheon, Republic of Korea, Eom, S.H., Kyung Hee University, Yongin, Republic of Korea, Lee, B.G., Korea Energy Technology, Seoul, Republic of Korea, Kang, W.S., Kangwon National University, Chuncheon, Republic of Korea, Cho, D.H., Kangwon National University, Chuncheon, Republic of Korea
Format: Article
Language:English
Subjects:
A549
anti-inflammatory
Antiinflammatory agents
Antioxidants
Antitumor activity
Cell proliferation
Chemistry
Chemistry and Materials Science
Chrysanthemum
Data processing
Drying
far infrared ray
Flavonoids
Flowers
Food Science
gamguk
Lipopolysaccharides
Lung cancer
Nitric oxide
Nutrition
phenolic compounds
POLIFENOLES
POLYPHENOL
POLYPHENOLS
Prostaglandin E2
Prostaglandin-endoperoxide synthase
Research Note
Shade
Tumors
식품과학
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Summary:This research demonstrated and compared the effects of shade and far infrared drying (FIRD) of gamguk (Chrysanthemum indicum L., CE) flowers extract on total phenolic (TP), total flavonoid (TF) content, anticancer and anti-inflammatory activities. The research data revealed that the TP and TF contents were highest in FIRD treated CE flower extracts. Similarly, the effect of CE on lipopolysaccharide (LPS) induced nitric oxide (NO) production in RAW264.7 cells showed in a dose dependent manner. Further, the CE inhibited the tumor necorsis factor (TNF)-α, cyclooxygenase (COX)-2 expression, and prostaglandis E₂ (PGE₂) production. The anticancer activity was monitored in A549 lung cancer cell, which showed that FIRD treated CE inhibited cell proliferation significantly (p less than 0.05) higher in dose and time dependent manner.
ISSN:1226-7708
2092-6456
DOI:10.1007/s10068-012-0034-0