Identification of Estrone in Pomegranate (Punica granatum) Extracts by Liquid Chromatography-Tandem Mass Spectrometry

There were some reports that the pomegranate juice, seeds, and peel extracts contain steroid hormones including estrone, but the results were controversial. This study was performed to identify estrone in pomegranate extracts through a more sensitive and validated technology. Separation and determin...

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Bibliographic Details
Published in:Food science and biotechnology 2010, 19(3), , pp.809-813
Main Authors: Kho, Y.L., Eulji University, Seongnam, Republic of Korea, Jung, W., Kyung Hee University, Seoul, Republic of Korea, Kwon, D.H., Hanil PFC Co., Ltd., Anseong, Republic of Korea, Kim, J.H., Eulji University, Seongnam, Republic of Korea
Format: Article
Language:English
Subjects:
Chemistry
Chemistry and Materials Science
ESTROGENOS
estrone
Food Science
GRANADA (FRUTA)
GRENADE (FRUITS)
liquid chromatography/mass spectrometry/mass spectrometry
Nutrition
OESTROGENE
OESTROGENS
phytochemical
POMEGRANATES
Punica granatum
Research Article
식품과학
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Summary:There were some reports that the pomegranate juice, seeds, and peel extracts contain steroid hormones including estrone, but the results were controversial. This study was performed to identify estrone in pomegranate extracts through a more sensitive and validated technology. Separation and determination of estrone was carried out using high performance liquid chromatography (HPLC) system with triple quadrupole mass spectrometry. Low concentration of estrone (4.5±0.38 ng/mL) was detected in pomegranate extracts with adequate precision value. The amount of estrone in pomegranate extracts was calculated as 16.4, 18.2, and 20.2 ng/mL, respectively, adjusted by extraction efficiency (average 25.6%) in the precision verification.
ISSN:1226-7708
2092-6456
DOI:10.1007/s10068-010-0113-z