Clinical Significance of Uptake Difference on DMSA Scintigraphy in Pediatric Urinary Tract Infection

Purpose Disruption of normal renal development can lead to congenital anomalies of the kidney and urinary tract, including renal hypodysplasia. We aimed to clarify whether small kidney size affects clinical manifestations in children with urinary tract infection (UTI). Methods One hundred fifty-four...

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Bibliographic Details
Published in:Childhood kidney diseases 2016, 20(2), , pp.63-68
Main Authors: Kim, Byung Kwan, Choi, Won Jee, Yim, Hyung Eun, Yoo, Kee Hwan
Format: Article
Language:English
Subjects:
acute pyelonephritis
dmsa scintigraphy
plasma ngal
small kidney
vesico-ureteral reflux
소아과학
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Summary:Purpose Disruption of normal renal development can lead to congenital anomalies of the kidney and urinary tract, including renal hypodysplasia. We aimed to clarify whether small kidney size affects clinical manifestations in children with urinary tract infection (UTI). Methods One hundred fifty-four patients who had their first symptomatic UTI between January 2014 and June 2015 were enrolled in this study. Differences in kidney size were estimated based on percent uptake of 99mTc-dimercaptosuccinic acid (DMSA) in scintigraphy. The patients who showed more than 10% difference in kidney size on DMSA scintigraphy with none or minimal cortical defects were included in group A. (group A, n=17). Laboratory, clinical, and imaging results were compared with those of the other patients (group B, n=137). Results Group A had a relatively higher incidence of vesicoureteral reflux than group B (44% vs 20%, P
ISSN:2384-0242
2384-0250
DOI:10.3339/jkspn.2016.20.2.63