Is Multi-Drug Resistant Tuberculosis More Prevalent in HIV-Infected Patients in Korea?

The epidemiological synergy between human immunodeficiency virus (HIV) and tuberculosis (TB) is a major threat to public health. However, the association between HIV and multi-drug resistant tuberculosis (MDR-TB) is not clear. To explore the association between HIV and MDR-TB infection, a case-contr...

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Bibliographic Details
Published in:Yonsei medical journal 2016, 57(6), , pp.1508-1510
Main Authors: Lee, Shinwon, Lee, Sun Hee, Mok, Jeong Ha, Lee, Su Jin, Kim, Kye Hyung, Lee, Jeong Eun, Lee, Seung Geun, Chung, Joo Seop, Kwak, Ihm Soo
Format: Article
Language:English
Subjects:
Adult
Antitubercular Agents - therapeutic use
Brief Communication
Case-Control Studies
Coinfection
Female
HIV Infections - complications
HIV Infections - drug therapy
HIV Infections - epidemiology
HIV Infections - microbiology
Humans
Male
Middle Aged
Mycobacterium tuberculosis - drug effects
Mycobacterium tuberculosis - isolation & purification
Prevalence
Republic of Korea - epidemiology
Tuberculosis, Multidrug-Resistant - complications
Tuberculosis, Multidrug-Resistant - epidemiology
Tuberculosis, Multidrug-Resistant - microbiology
Tuberculosis, Pulmonary - diagnosis
Tuberculosis, Pulmonary - drug therapy
Tuberculosis, Pulmonary - epidemiology
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Summary:The epidemiological synergy between human immunodeficiency virus (HIV) and tuberculosis (TB) is a major threat to public health. However, the association between HIV and multi-drug resistant tuberculosis (MDR-TB) is not clear. To explore the association between HIV and MDR-TB infection, a case-control study was performed in Korea. A total of 1606 culture-proven TB patients (45 HIV vs. 1561 non-HIV) from January 2006 to October 2014 were included in this analysis. MDR-TB rates were 11.1% and 8.2% in the HIV and non-HIV groups, respectively (p=0.42), thus indicating that MDR-TB was not significantly associated with HIV infection in Korea.
ISSN:0513-5796
1976-2437
DOI:10.3349/ymj.2016.57.6.1508