Acute interstitial nephritis induced by Solanum nigrum

Abstract Acute interstitial nephritis (AIN) is an important cause of reversible acute kidney injury and is pathologically characterized by inflammatory infiltrate in the renal interstitium. Solanum nigrum ( S. nigrum ) is a medicinal plant member of the Solanaceae family. While S. nigrum has been tr...

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Bibliographic Details
Published in:Kidney research and clinical practice 2016, 35(4), , pp.252-254
Main Authors: Oh, Sung Sik, Choi, Myung Woo, Lee, Jong Hwa, Yang, Hyun Ju, Choi, Yeong Jin, Lee, Kwang Young, Sun, In O., MD
Format: Article
Language:English
Subjects:
Acute interstitial nephritis
Case Report
Corticosteroid
Nephrology
Solanum
내과학
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Summary:Abstract Acute interstitial nephritis (AIN) is an important cause of reversible acute kidney injury and is pathologically characterized by inflammatory infiltrate in the renal interstitium. Solanum nigrum ( S. nigrum ) is a medicinal plant member of the Solanaceae family. While S. nigrum has been traditionally used to treat various ailments such as pain, inflammation, and fever, it has also been reported to have a toxic effect, resulting in anticholinergic symptoms. However, there have been no reports of AIN caused by S. nigrum . Here, we report the first case of biopsy-confirmed AIN following ingestion of S. nigrum . The patient was successfully treated using corticosteroid therapy.
ISSN:2211-9132
2211-9140
DOI:10.1016/j.krcp.2016.05.003