Relationship between serum IgA level and allergy/asthma

Mucosal immunoglobulin A (IgA) may prevent the entrance of allergens. This study examined the relationship between serum IgA levels (within the normal range) and sensitization to house dust mites (HDM) or airway hyper-responsiveness (AHR). The clinical records of 1,136 adult patients with suspected...

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Bibliographic Details
Published in:The Korean journal of internal medicine 2017, 32(1), , pp.137-145
Main Authors: Kim, Woo-Jin, Choi, Inseon S, Kim, Chang Seong, Lee, Jeong-Hyeon, Kang, Hyeon-Wook
Format: Article
Language:English
Subjects:
Adult
Animals
Asthma - blood
Asthma - diagnosis
Asthma - immunology
Biomarkers - blood
Bronchial Hyperreactivity - blood
Bronchial Hyperreactivity - diagnosis
Bronchial Hyperreactivity - immunology
Bronchial Provocation Tests
Chi-Square Distribution
Female
Humans
Hypersensitivity - blood
Hypersensitivity - diagnosis
Hypersensitivity - immunology
Immunoglobulin A - blood
Intradermal Tests
Linear Models
Logistic Models
Male
Middle Aged
Odds Ratio
Original
Predictive Value of Tests
Pyroglyphidae - immunology
Retrospective Studies
Risk Factors
Severity of Illness Index
내과학
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Summary:Mucosal immunoglobulin A (IgA) may prevent the entrance of allergens. This study examined the relationship between serum IgA levels (within the normal range) and sensitization to house dust mites (HDM) or airway hyper-responsiveness (AHR). The clinical records of 1,136 adult patients with suspected asthma, for whom test data for serum IgA level and methacholine-AHR were available, were reviewed retrospectively. The AHR/allergy indices were compared among patient groups with low (
ISSN:1226-3303
2005-6648
DOI:10.3904/kjim.2014.160