높은 Ki-67 발현을 보이며 빠르게 진행한 소장 림프종 1예

• Published in: The Korean journal of helicobacter and upper gastrointestinal research 2017, 17(1), , pp.49-53
• Main Authors: 유지연, 강희준, 김형근, 한수정, 오승현, 정성훈, 오정환, 전은정
• Format: Article
• Language: Korean
• Subjects: 내과학
• ISSN: 1738-3331; 2671-826X
• DOI: 10.7704/kjhugr.2017.17.1.

Primary intestinal lymphoma is a rare disease. It accounts for approximately 1∼4% of gastrointestinal malignancy. Extranodal lymphoma of the intestine mainly arises from B cells. Diffuse large B-cell lymphoma is the most common type of the disease. Approximately 40% of intestinal lymphoma can be cured, while 60% have varied disease progression. Ki-67 proliferation has been recently used as an index of cell growth to predict the progression of the disease. Reported herein is a case of a rapidly progressive small bowel diffuse large B-cell lymphoma in a 51-year-old man with a high Ki-67 expression level. He visited the emergency department because of hematochezia. Abdominal computed tomography revealed distal small bowel segmental wall thickening. He underwent operation due to spontaneous small bowel perforation. The result of the pathological examination of the resected specimen was compatible with diffuse large B-cell lymphoma. The Ki-67 index within 5 months was 90%. (Korean J Helicobacter Up Gastrointest Res 2017;17:-53) KCI Citation Count: 0