HELLP syndrome in a pregnant patient with Gitelman syndrome

Gitelman syndrome is characterized by hypokalemia, metabolic alkalosis, hypocalciuria, and hypomagnesemia. The clinical course of Gitelman syndrome in pregnant women remains unclear, but it is thought to be benign. We report here the first Korean case of atypical eclampsia in a 31-year-old who was d...

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Bibliographic Details
Published in:Kidney research and clinical practice 2017, 36(1), , pp.95-99
Main Authors: Lee, Minhyeok, Kim, Dong-Il, Lee, Kyung-Ho, Byun, Jun-Hyun, Hwang, Jiyong, Hwang, Won-Min, Yun, Sung-Ro, Yoon, Se-Hee
Format: Article
Language:English
Subjects:
Case Report
Eclampsia
Gitelman syndrome
HELLP syndrome
Pregnancy
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Summary:Gitelman syndrome is characterized by hypokalemia, metabolic alkalosis, hypocalciuria, and hypomagnesemia. The clinical course of Gitelman syndrome in pregnant women remains unclear, but it is thought to be benign. We report here the first Korean case of atypical eclampsia in a 31-year-old who was diagnosed with Gitelman syndrome incidentally during an antenatal screening test. The patient did well during pregnancy despite significant hypokalemia. At 33 weeks' gestation, the patient exhibited eclampsia, hemolysis, elevated liver enzymes, low platelets (HELLP) syndrome, and renal insufficiency without significant hypertension or proteinuria. We explain this unusual clinical course through a review of the relevant literature.
ISSN:2211-9132
2211-9140
DOI:10.23876/j.krcp.2017.36.1.95