Are There Relationships between Seminal Parameters and the Neutrophil-to-Lymphocyte Ratio or the Platelet-to-Lymphocyte Ratio?

• Published in: The world journal of men's health 2017, 35(1), , pp.51-56
• Main Authors: Aykan, Serdar, Canat, Lütfi, Gönültaş, Serkan, Atalay, Hasan Anıl, Altunrende, Fatih
• Format: Article
• Language: English
• Subjects: Abstinence; Blood; Blood platelets; Body mass index; Clinical medicine; Conflicts of interest; Cytokines; Fertility; Hematology; Infertility; Inflammation; Inflammatory diseases; Lymphocytes; Morphology; Motility; Neutrophils; Original; Pathophysiology; Semen analysis; Sperm; Tumor necrosis factor-TNF; 비뇨기과학
• ISSN: 2287-4208; 2287-4690
• DOI: 10.5534/wjmh.2017.35.1.51

The aim of this study was to evaluate the relationship of seminal parameters with the neutrophil-to-lymphocyte ratio (NLR) and the platelet-to-lymphocyte ratio (PLR), which are inflammatory markers, in men with an abnormal semen analysis and men with normozoospermia. Fifty-seven men with abnormal semen analyses and 59 men with normozoospermia were included in this cross-sectional study. A complete blood count was recorded, and the NLR and PLR were calculated from the hematologic parameters. The NLR was 1.84±0.78 in the normozoospermic group and 1.80±0.75 in the abnormal semen analysis group. The PLR was 95.32±35.47 in the normozoospermic group and 93.57±28.09 in the abnormal semen analysis group. No significant differences were found between the normozoospermic and the abnormal semen analysis group in the NLR (p=0.828) or the PLR (p=0.768). In addition, no seminal parameters were correlated with the NLR or the PLR (p>0.05). We do not recommend using the NLR or the PLR as markers to screen for abnormal semen parameters or male infertility.