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Ophthalmologic Features of Lennox-Gastaut Syndrome
To describe the characteristics and frequency of ophthalmologic findings in patients with Lennox-Gastaut syndrome (LGS). The medical records of patients diagnosed with LGS at Seoul National University Children's Hospital from January 2004 to August 2014 were retrospectively reviewed. The record...
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Published in: | Korean journal of ophthalmology 2017, 31(3), , pp.263-267 |
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creator | Kim, Bo Hee Yu, Young Suk Kim, Seong Joon |
description | To describe the characteristics and frequency of ophthalmologic findings in patients with Lennox-Gastaut syndrome (LGS).
The medical records of patients diagnosed with LGS at Seoul National University Children's Hospital from January 2004 to August 2014 were retrospectively reviewed. The records of 34 patients (mean age ± standard deviation, 2.66 ± 3.51 years; male, 58.8%) were reviewed. The primary measure was the incidence of ophthalmologic manifestations.
Of the 34 patients, 88.2% had at least one ocular abnormality. Refractive error (52.9%) was the most frequently observed ophthalmologic manifestation in patients with LGS, followed by strabismus (32.4%), cortical visual impairment (23.5%), and retinopathy of prematurity (8.8%). Among these cases, seven patients had exotropia and three had esotropia.
LGS is a childhood-onset epileptic encephalopathy with variable ophthalmologic manifestations, the most frequent being refractive errors. Patients with suspected LGS should be examined regularly because ophthalmological features can change during their disease course. |
doi_str_mv | 10.3341/kjo.2015.0161 |
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The medical records of patients diagnosed with LGS at Seoul National University Children's Hospital from January 2004 to August 2014 were retrospectively reviewed. The records of 34 patients (mean age ± standard deviation, 2.66 ± 3.51 years; male, 58.8%) were reviewed. The primary measure was the incidence of ophthalmologic manifestations.
Of the 34 patients, 88.2% had at least one ocular abnormality. Refractive error (52.9%) was the most frequently observed ophthalmologic manifestation in patients with LGS, followed by strabismus (32.4%), cortical visual impairment (23.5%), and retinopathy of prematurity (8.8%). Among these cases, seven patients had exotropia and three had esotropia.
LGS is a childhood-onset epileptic encephalopathy with variable ophthalmologic manifestations, the most frequent being refractive errors. Patients with suspected LGS should be examined regularly because ophthalmological features can change during their disease course.</description><identifier>ISSN: 1011-8942</identifier><identifier>EISSN: 2092-9382</identifier><identifier>DOI: 10.3341/kjo.2015.0161</identifier><identifier>PMID: 28471101</identifier><language>eng</language><publisher>Korea (South): The Korean Ophthalmological Society</publisher><subject>Adolescent ; Brain - pathology ; Child ; Child, Preschool ; Eye Movements - physiology ; Female ; Humans ; Infant ; Infant, Newborn ; Lennox Gastaut Syndrome - complications ; Lennox Gastaut Syndrome - diagnosis ; Magnetic Resonance Imaging ; Male ; Original ; Refraction, Ocular - physiology ; Refractive Errors - diagnosis ; Refractive Errors - etiology ; Refractive Errors - physiopathology ; Strabismus - diagnosis ; Strabismus - etiology ; Strabismus - physiopathology ; Vision Tests ; Visual Acuity ; 안과학</subject><ispartof>Korean Journal of Ophthalmology, 2017, 31(3), , pp.263-267</ispartof><rights>2017 The Korean Ophthalmological Society</rights><rights>2017 The Korean Ophthalmological Society 2017</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c2661-626d4e98b5d0e93cac56149a9f80c269050ee5e34202fea0be2b75b5577e91433</citedby><cites>FETCH-LOGICAL-c2661-626d4e98b5d0e93cac56149a9f80c269050ee5e34202fea0be2b75b5577e91433</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5469930/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5469930/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28471101$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttps://www.kci.go.kr/kciportal/ci/sereArticleSearch/ciSereArtiView.kci?sereArticleSearchBean.artiId=ART002227618$$DAccess content in National Research Foundation of Korea (NRF)$$Hfree_for_read</backlink></links><search><creatorcontrib>Kim, Bo Hee</creatorcontrib><creatorcontrib>Yu, Young Suk</creatorcontrib><creatorcontrib>Kim, Seong Joon</creatorcontrib><title>Ophthalmologic Features of Lennox-Gastaut Syndrome</title><title>Korean journal of ophthalmology</title><addtitle>Korean J Ophthalmol</addtitle><description>To describe the characteristics and frequency of ophthalmologic findings in patients with Lennox-Gastaut syndrome (LGS).
The medical records of patients diagnosed with LGS at Seoul National University Children's Hospital from January 2004 to August 2014 were retrospectively reviewed. The records of 34 patients (mean age ± standard deviation, 2.66 ± 3.51 years; male, 58.8%) were reviewed. The primary measure was the incidence of ophthalmologic manifestations.
Of the 34 patients, 88.2% had at least one ocular abnormality. Refractive error (52.9%) was the most frequently observed ophthalmologic manifestation in patients with LGS, followed by strabismus (32.4%), cortical visual impairment (23.5%), and retinopathy of prematurity (8.8%). Among these cases, seven patients had exotropia and three had esotropia.
LGS is a childhood-onset epileptic encephalopathy with variable ophthalmologic manifestations, the most frequent being refractive errors. Patients with suspected LGS should be examined regularly because ophthalmological features can change during their disease course.</description><subject>Adolescent</subject><subject>Brain - pathology</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Eye Movements - physiology</subject><subject>Female</subject><subject>Humans</subject><subject>Infant</subject><subject>Infant, Newborn</subject><subject>Lennox Gastaut Syndrome - complications</subject><subject>Lennox Gastaut Syndrome - diagnosis</subject><subject>Magnetic Resonance Imaging</subject><subject>Male</subject><subject>Original</subject><subject>Refraction, Ocular - physiology</subject><subject>Refractive Errors - diagnosis</subject><subject>Refractive Errors - etiology</subject><subject>Refractive Errors - physiopathology</subject><subject>Strabismus - diagnosis</subject><subject>Strabismus - etiology</subject><subject>Strabismus - physiopathology</subject><subject>Vision Tests</subject><subject>Visual Acuity</subject><subject>안과학</subject><issn>1011-8942</issn><issn>2092-9382</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><recordid>eNpVkctLw0AQhxdRtFaPXqVHPaTOPpO9CFJ8FAqCj_OySSY2NsnW3UTsf2_6UPQ0h983vxn4CDmjMOZc0KvFuxszoHIMVNE9MmCgWaR5wvbJgAKlUaIFOyLHIbwDKMohPiRHLBEx7dMBYY_LeTu3Ve0q91Zmozu0becxjFwxmmHTuK_o3obWdu3oedXk3tV4Qg4KWwU83c0heb27fZk8RLPH--nkZhZlTCkaKaZygTpJZQ6oeWYzqajQVhcJ9IQGCYgSuWDACrSQIktjmUoZx6ip4HxILre9jS_MIiuNs-Vmvjmz8Obm6WVqKI-10qpnr7fssktrzDNsWm8rs_Rlbf1qs_k_acp53_NppFBac-gLLnYF3n10GFpTlyHDqrINui4YmmjJ4lgA69Foi2beheCx-D1DwaydmN6JWTsxayc9f_73t1_6RwL_BlJ7hrY</recordid><startdate>201706</startdate><enddate>201706</enddate><creator>Kim, Bo Hee</creator><creator>Yu, Young Suk</creator><creator>Kim, Seong Joon</creator><general>The Korean Ophthalmological Society</general><general>대한안과학회</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope><scope>ACYCR</scope></search><sort><creationdate>201706</creationdate><title>Ophthalmologic Features of Lennox-Gastaut Syndrome</title><author>Kim, Bo Hee ; Yu, Young Suk ; Kim, Seong Joon</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c2661-626d4e98b5d0e93cac56149a9f80c269050ee5e34202fea0be2b75b5577e91433</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Adolescent</topic><topic>Brain - pathology</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>Eye Movements - physiology</topic><topic>Female</topic><topic>Humans</topic><topic>Infant</topic><topic>Infant, Newborn</topic><topic>Lennox Gastaut Syndrome - complications</topic><topic>Lennox Gastaut Syndrome - diagnosis</topic><topic>Magnetic Resonance Imaging</topic><topic>Male</topic><topic>Original</topic><topic>Refraction, Ocular - physiology</topic><topic>Refractive Errors - diagnosis</topic><topic>Refractive Errors - etiology</topic><topic>Refractive Errors - physiopathology</topic><topic>Strabismus - diagnosis</topic><topic>Strabismus - etiology</topic><topic>Strabismus - physiopathology</topic><topic>Vision Tests</topic><topic>Visual Acuity</topic><topic>안과학</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kim, Bo Hee</creatorcontrib><creatorcontrib>Yu, Young Suk</creatorcontrib><creatorcontrib>Kim, Seong Joon</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>Korean Citation Index</collection><jtitle>Korean journal of ophthalmology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kim, Bo Hee</au><au>Yu, Young Suk</au><au>Kim, Seong Joon</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Ophthalmologic Features of Lennox-Gastaut Syndrome</atitle><jtitle>Korean journal of ophthalmology</jtitle><addtitle>Korean J Ophthalmol</addtitle><date>2017-06</date><risdate>2017</risdate><volume>31</volume><issue>3</issue><spage>263</spage><epage>267</epage><pages>263-267</pages><issn>1011-8942</issn><eissn>2092-9382</eissn><abstract>To describe the characteristics and frequency of ophthalmologic findings in patients with Lennox-Gastaut syndrome (LGS).
The medical records of patients diagnosed with LGS at Seoul National University Children's Hospital from January 2004 to August 2014 were retrospectively reviewed. The records of 34 patients (mean age ± standard deviation, 2.66 ± 3.51 years; male, 58.8%) were reviewed. The primary measure was the incidence of ophthalmologic manifestations.
Of the 34 patients, 88.2% had at least one ocular abnormality. Refractive error (52.9%) was the most frequently observed ophthalmologic manifestation in patients with LGS, followed by strabismus (32.4%), cortical visual impairment (23.5%), and retinopathy of prematurity (8.8%). Among these cases, seven patients had exotropia and three had esotropia.
LGS is a childhood-onset epileptic encephalopathy with variable ophthalmologic manifestations, the most frequent being refractive errors. Patients with suspected LGS should be examined regularly because ophthalmological features can change during their disease course.</abstract><cop>Korea (South)</cop><pub>The Korean Ophthalmological Society</pub><pmid>28471101</pmid><doi>10.3341/kjo.2015.0161</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Adolescent Brain - pathology Child Child, Preschool Eye Movements - physiology Female Humans Infant Infant, Newborn Lennox Gastaut Syndrome - complications Lennox Gastaut Syndrome - diagnosis Magnetic Resonance Imaging Male Original Refraction, Ocular - physiology Refractive Errors - diagnosis Refractive Errors - etiology Refractive Errors - physiopathology Strabismus - diagnosis Strabismus - etiology Strabismus - physiopathology Vision Tests Visual Acuity 안과학 |
title | Ophthalmologic Features of Lennox-Gastaut Syndrome |
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