Mean platelet volume and vitamin D level

Vitamin D deficiency and a high mean platelet volume (MPV) are related to cardiovascular disease. We investigated whether vitamin D deficiency is associated with high MPV. This study included 434 patients without chronic disease who were not taking vitamin D or calcium supplements. Vitamin D was mea...

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Bibliographic Details
Published in:Annals of laboratory medicine 2014, 34(2), , pp.98-103
Main Authors: Cumhur Cure, Medine, Cure, Erkan, Yuce, Suleyman, Yazici, Tarkan, Karakoyun, Inanc, Efe, Hasan
Format: Article
Language:English
Subjects:
Adolescent
Adult
Age Factors
Aged
Aged, 80 and over
Blood Glucose - analysis
Blood Platelets - cytology
Cell Size
Female
Humans
Immunoassay
Luminescent Measurements
Male
Middle Aged
Original
Vitamin D - analysis
Vitamin D Deficiency - metabolism
Vitamin D Deficiency - pathology
Young Adult
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Summary:Vitamin D deficiency and a high mean platelet volume (MPV) are related to cardiovascular disease. We investigated whether vitamin D deficiency is associated with high MPV. This study included 434 patients without chronic disease who were not taking vitamin D or calcium supplements. Vitamin D was measured by chemiluminescent microparticle immunoassay on the Architect-I2000 system (Abbott Diagnostics, USA), and MPV was measured on the Cell-Dyn Ruby analyzer (Abbott Diagnostics). Patients were divided into Groups 1 (138 [men/women, 46/92]), 2 (148 [men/women, 54/94]), and 3 (148 [men/women, 50/98]) according to vitamin D levels of 20 ng/mL, respectively. The vitamin D level in Group 1 (7.7±1.9 ng/mL) was lower than that in Group 2 (15.1±1.6 ng/mL, P
ISSN:2234-3806
2234-3814
DOI:10.3343/alm.2014.34.2.98