Effects of various toothpastes on remineralization of white spot lesions

• Published in: Korean journal of orthodontics (2012) 2014, 44(3), , pp.113-118
• Main Authors: Jo, Su-Yeon, Chong, Hyun-Jeong, Lee, Eon-Hwa, Chang, Na-Young, Chae, Jong-Moon, Cho, Jin-Hyoung, Kim, Sang-Cheol, Kang, Kyung-Hwa
• Format: Article
• Language: English
• Subjects: Original; 치의학
• ISSN: 2234-7518; 2005-372X
• DOI: 10.4041/kjod.2014.44.3.113

The purpose of this in vitro study was to examine the effects of fluoridated, casein phosphopeptide.amorphous calcium phosphate complex (CPP-ACP)-containing, and functionalized β-tricalcium phosphate (fTCP)-containing toothpastes on remineralization of white spot lesions (WSLs) by using Quantitative light-induced fluorescence (QLF-D) Biluminator™ 2. Forty-eight premolars, extracted for orthodontic reasons from 12 patients, with artificially induced WSLs were randomly and equally assigned to four treatment groups: fluoride (1,000 ppm), CPP-ACP, fTCP (with sodium fluoride), and control (deionized water) groups. Specimens were treated twice daily for 2 weeks and stored in saliva solution (1:1 mixture of artificial and human stimulated saliva) otherwise. QLF-D Biluminator™ 2 was used to measure changes in fluorescence, indicating alterations in the mineral contents of the WSLs, immediately before and after the 2 weeks of treatment. Fluorescence greatly increased in the fTCP and CPP-ACP groups compared with the fluoride and control groups, which did not show significant differences. fTCP- and CPP-ACP-containing toothpastes seem to be more effective in reducing WSLs than 1,000-ppm fluoride-containing toothpastes.