Pulmonary cryptococcosis mimicking primary lung cancer with multiple lung metastases

Cryptococcosis is an invasive fungal infection, which is more common in immunocompromised patients. However, pulmonary cryptococcosis can occur in immunocompetent patients and should be considered on a differential diagnosis for nodular or mass-like lesions in chest radiograph. Recently, we experien...

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Published in:Tuberculosis and respiratory diseases 2012, 73(3), 332, pp.182-186
Main Authors: Kim, Yu Seung, Lee, In Hee, Kim, Hyun Seon, Jin, Su Sin, Lee, Jong Hwan, Kim, Sung-Kyoung, Song, So Hyang, Yoo, Jinyoung, Kim, Chi Hong, Kwon, Soon Seog
Format: Article
Language:English
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Summary:Cryptococcosis is an invasive fungal infection, which is more common in immunocompromised patients. However, pulmonary cryptococcosis can occur in immunocompetent patients and should be considered on a differential diagnosis for nodular or mass-like lesions in chest radiograph. Recently, we experienced a patient with pulmonary cryptococcosis, successfully treated with oral fluconazole therapy. A 74-year-old female patient was referred for an evaluation of abnormal images, a large consolidative mass with multiple nodular consolidations and small nodules that mimics primary lung cancer with multiple lung to lung metastases. Computed tomography-guided lung biopsy confirmed the diagnosis of pulmonary cryptococcosis. The follow-up image taken after 4 months with oral fluconazole treatment showed marked improvement.
ISSN:1738-3536
2005-6184
DOI:10.4046/trd.2012.73.3.182