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Drug rash with eosinophilia and systemic symptoms syndrome induced by chloral hydrate in early childhood

Drug rash with eosinophilia and systemic symptoms (DRESS) syndrome, also known as drug-induced hypersensitivity syndrome (DIHS), is a rare, acute and severe life-threatening systemic disease. DRESS syndrome is characterized by fever, lymphadenopathy, rash, hypereosinophilia and involvement of system...

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Published in:Allergy, asthma & immunology research 2014, Asthma & Immunology Research, 6(3), , pp.270-272
Main Authors: Yoo, Suk Dong, Kim, Su Gon, Kim, Seong Heon, Kim, Hye-Young
Format: Article
Language:English
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Summary:Drug rash with eosinophilia and systemic symptoms (DRESS) syndrome, also known as drug-induced hypersensitivity syndrome (DIHS), is a rare, acute and severe life-threatening systemic disease. DRESS syndrome is characterized by fever, lymphadenopathy, rash, hypereosinophilia and involvement of systemic organs. The most commonly implicated drugs are anticonvulsants, sulfonamides and allopurinol. Chloral hydrate is a sedative and hypnotic drug frequently used in pediatric patients. We first report a case of DRESS syndrome induced by chloral hydrate in a 14-month-old female.
ISSN:2092-7355
2092-7363
DOI:10.4168/aair.2014.6.3.270