Multimodal treatment of primary extraskeletal Ewing's sarcoma of the chest wall: report of 2 cases

• Published in: Cancer research and treatment 2009, 41(2), , pp.108-112
• Main Authors: Lee, Woo Surng, Kim, Yo Han, Chee, Hyun Keun, Hwang, Jae Joon, Kim, Jun Seok, Lee, Song Am, Hwang, Eun Gu, Cho, Yo Han, Chon, Gyu Rak
• Format: Article
• Language: English
• Subjects: Case Report; 의약학
• ISSN: 1598-2998; 2005-9256
• DOI: 10.4143/crt.2009.41.2.108

Extraskeletal Ewing's sarcoma (EES) is a type of Ewing's sarcoma that arises in soft tissue and is now regarded as a member of a family of small round cell neoplasms of bone and soft tissue, including primitive neuroectodermal tumors (PNETs). EES occurs predominantly in adolescents and young adults between the ages of 10 and 30 years. The disease follows an aggressive course with a high recurrence rate. The presence of a distant metastasis is also common. EES arises in the soft tissue of either the trunk or extremities. We recently experienced two cases of EES that occurred in the chest wall. The two patients underwent wide resection and combined radiochemotherapy. There was no evidence of disease 30 and 22 months, respectively, after surgery. Although extremely rare, EES should be considered in the differential diagnosis of chest wall tumors. We report two cases of EES with a brief review of the literature.