Antioxidant and antidiabetic activities of extracts from Cirsium japonicum roots

This study investigated the antioxidant activity of methanol (MeOH) and water extracts from roots of Cirsium japonicum in vitro, MeOH extract showed a stronger tree radical scavenging activity than water extract. However, both of extracts showed a concentration dependent hydroxyl radical scavenging...

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Published in:Nutrition research and practice 2008, 2(4), , pp.247-251
Main Authors: Yin, Jie (Kangwon National University, Chuncheon, Republic of Korea), Heo, S.I. (Kangwon National University, Chuncheon, Republic of Korea), Wang, M.H. (Kangwon National University, Chuncheon, Republic of Korea), E-mail: mhwang@kangwon.ac.kr
Format: Article
Language:English
Subjects:
antidiabetic
ANTIOXIDANTES
ANTIOXIDANTS
ANTIOXYDANT
Cirsium japonicum
methanol and water extracts
Original Research
생활과학
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Summary:This study investigated the antioxidant activity of methanol (MeOH) and water extracts from roots of Cirsium japonicum in vitro, MeOH extract showed a stronger tree radical scavenging activity than water extract. However, both of extracts showed a concentration dependent hydroxyl radical scavenging activity, reducing power and metal chelating ability, MeOH extract had greater phenolic and flavonoid contents than water extract. The antidiabetic activity of these two extracts was evaluated by the α-glucosidase inhibition assay, The water extract showed a considerable α-glucosidase inhibitory activity. To our knowledge, this may be the first time to report the antioxidant and antidiabetic activities in Cirsium japonicum roots.
ISSN:1976-1457
2005-6168
DOI:10.4162/nrp.2008.2.4.247