Stroke mimicking encephalopathy as an initial manifestation of diffuse large B-cell lymphoma

Systemic lymphoma can be difficult to recognize due to its diverse manifestations. Paraneoplastic leukoencephalopathy has rarely been reported in the context of lymphoma. We report a 45-year-old man with systemic lymphoma whose initial manifestation was sudden-onset leukoencephalopathy, mimicking st...

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Bibliographic Details
Published in:Journal of clinical neurology (Seoul, Korea) 2009, 5(2), , pp.97-100
Main Authors: Kim, Jeong-Min, Jung, Keun-Hwa, Lee, Soon-Tae, Park, Hee-Kwon, Chu, Kon, Roh, Jae-Kyu
Format: Article
Language:English
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Case Report
신경과학
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Summary:Systemic lymphoma can be difficult to recognize due to its diverse manifestations. Paraneoplastic leukoencephalopathy has rarely been reported in the context of lymphoma. We report a 45-year-old man with systemic lymphoma whose initial manifestation was sudden-onset leukoencephalopathy, mimicking stroke. This patient, who was eventually diagnosed with diffuse large B-cell lymphoma, initially presented with sudden cognitive impairment and gait disturbance. Radiological studies suggested a paraneoplastic leukoencephalopathy. Chemotherapy for lymphoma resulted in clinical and radiological improvement. The presented case indicates that diffuse large B-cell lymphoma may initially appear as a treatable leukoencephalopathy.
ISSN:1738-6586
2005-5013
DOI:10.3988/jcn.2009.5.2.97