Histopathological and biochemical findings of congenital copper deficiency: are these similar to those of caprine arthritis-encephalitis?

• Published in: Journal of veterinary science (Suwŏn-si, Korea) 2012, 13(1), , pp.107-109
• Main Authors: Ozkul, I. Ayhan, Ankara University, Ankara, Turkey, Alcigir, G., Ankara University, Ankara, Turkey, Sepici-Dincel, A., Gazi University, Ankara, Turkey, Yonguc, A. D., Veterinary Control Central Research Institute, Ankara, Turkey, Akcora, A., Veterinary Control Central Research Institute, Ankara, Turkey, Turkaslan, J., Veterinary Control Central Research Institute, Istanbul, Turkey
• Format: Article
• Language: English
• Subjects: Animals; Animals, Newborn; arthritis-encephalitis; CAPRIN; CAPRINOS; Carpal Joints - metabolism; Carpal Joints - pathology; Case Report; congenital copper deficiency; Copper - blood; Copper - deficiency; Copper - metabolism; Female; Goat Diseases - congenital; Goat Diseases - metabolism; Goat Diseases - pathology; GOATS; HISTOPATHOLOGIE; HISTOPATHOLOGY; HISTOPATOLOGIA; Joint Diseases - congenital; Joint Diseases - metabolism; Joint Diseases - pathology; Joint Diseases - veterinary; Male; Pregnancy; twisted carpal joints; 수의학
• ISSN: 1229-845X; 1976-555X
• DOI: 10.4142/jvs.2012.13.1.107

This study was done after identifying animals with a twisted carpal joint in goat herd. These included a kid goat walking on its articulus carpii and a newborn goat with a stiff leg. Necropsies of the diseased goats revealed swollen carpal joints that were twisted backwards. Arthritis was observed during microscopic examination of the carpal joints. Very low levels of eosinophil, leucocyte, and lymphocyte cell infiltration were found in the central nervous system and meninges. Serum copper levels were significantly decreased in most of the animals. All of these results led us to diagnose the animals with swayback disease.