Effectiveness of ∨99mTC-tetrofosmin for assessment of heart functions in micropigs

• Published in: Journal of veterinary science (Suwŏn-si, Korea) 2007, 8(3), , pp.223-227
• Main Authors: Lee, M.Y. (Chonnam National University, Gwangju, Republic of Korea), Lee, S.H. (Chonnam National University, Gwangju, Republic of Korea), Park, J.H. (Chonnam National University, Gwangju, Republic of Korea), Heo, J.H. (Chonnam National University, Gwangju, Republic of Korea), Lee, Y.J. (Chonnam National University, Gwangju, Republic of Korea), Suh, H.N. (Chonnam National University, Gwangju, Republic of Korea), Min, J.J. (Chonnam National University Hwasun Hospital, Hwasun, Republic of Korea), Seo, Y.S. (Chonnam National University Hwasun Hospital, Hwasun, Republic of Korea), Han, H.J. (Chonnam National University, Gwangju, Republic of Korea), E-mail: [e-mail]
• Format: Article
• Language: English
• Subjects: ejection fraction (EF); heart function; micropig; Original; TRANSPLANTATION; TRASPLANTES; 수의학
• ISSN: 1229-845X; 1976-555X
• DOI: 10.4142/jvs.2007.8.3.223

This study examined the suitability of a nuclear imaging technique using ∨99mTC-tetrofosmin as an agent to assess the heart functions of healthy micropigs. The mean age of the pigs was 360 days (male), and the mean body weight was 35.3 kg ranging from 34.5-36 kg. There were no significant perfusion defects in any of the reconstructed images. Gated single-photon emission computed tomography imaging can be used to calculate the ventricular volume and ejection fraction (EF). In this case, an EF of 79% was calculated from the ventricular volume of the end-systolic image (10 ml) subtracted from that of the end-diastolic volume (49 ml).