Usefulness of neutrophil-lymphocyte ratio in young children with febrile urinary tract infection

Acute pyelonephritis (APN) is a serious bacterial infection that can cause renal scarring in children. Early identification of APN is critical to improve treatment outcomes. The neutrophil-lymphocyte ratio (NLR) is a prognostic marker of many diseases, but it has not yet been established in urinary...

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Bibliographic Details
Published in:Clinical and experimental pediatrics 2016, 59(3), , pp.139-144
Main Authors: Han, Song Yi, Lee, I Re, Park, Se Jin, Kim, Ji Hong, Shin, Jae Il
Format: Article
Language:English
Subjects:
Antibiotics
Bacterial infections
Biomarkers
Bladder
Blood
Child
Defects
Hydronephrosis
Kidney diseases
Laboratories
Lymphocytes
Neutrophil-lymphocyte ratio
Neutrophils
Original
Pyelonephritis
Regression analysis
Urinary tract diseases
Urinary tract infections
Urine
Urogenital system
Vesico-ureteral reflux
소아과학
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Summary:Acute pyelonephritis (APN) is a serious bacterial infection that can cause renal scarring in children. Early identification of APN is critical to improve treatment outcomes. The neutrophil-lymphocyte ratio (NLR) is a prognostic marker of many diseases, but it has not yet been established in urinary tract infection (UTI). The aim of this study was to determine whether NLR is a useful marker to predict APN or vesicoureteral reflux (VUR). We retrospectively evaluated 298 pediatric patients (age≤36 months) with febrile UTI from January 2010 to December 2014. Conventional infection markers (white blood cell [WBC] count, erythrocyte sedimentation rate [ESR], C-reactive protein [CRP]), and NLR were measured. WBC, CRP, ESR, and NLR were higher in APN than in lower UTI (P
ISSN:1738-1061
2092-7258
2713-4148
DOI:10.3345/kjp.2016.59.3.139