Treatment of juvenile rheumatoid arthritis

The systematic approach to pharmacologic treatment is typically to begin with the safest, simplest, and most conservative measures. It has been realized that the more rapidly inflammation is under control, the less likely it is that there will be permanent sequelae. Nonsteroidal anti-inflammatory dr...

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Bibliographic Details
Published in:Clinical and experimental pediatrics 2010, 53(11), , pp.936-941
Main Author: Kim, Kwang Nam
Format: Article
Language:English
Subjects:
Anti-inflammatory agents
Arthritis
Aspirin
Child
Children & youth
Disease modifying antirheumatic drugs
Drug dosages
Drug withdrawal
Food
Inflammation
Juvenile arthritis
Non-steroidal anti-inflammatory agents
Nonsteroidal anti-inflammatory drugs
Oral administration
Remission (Medicine)
Review
Steroids
Systemic diseases
Therapy
Toxicity
소아과학
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Summary:The systematic approach to pharmacologic treatment is typically to begin with the safest, simplest, and most conservative measures. It has been realized that the more rapidly inflammation is under control, the less likely it is that there will be permanent sequelae. Nonsteroidal anti-inflammatory drugs (NSAIDs) are the mainstay of initial treatment for inflammation. In addition, the slow-acting antirheumatic drugs (SAARDs) and disease-modifying antirheumatic drugs (DMARDs) have efficacy of anti-inflammatory action in children with chronic arthritis. New therapeutic modalities for inflammation, such as etanercept and infliximab, promise even further improvements in the risk/benefit ratio of treatment. It is not typically possible at the onset of the disease to predict which children will recover and which will go on to have unremitting disease with lingering disability or enter adulthood with serious functional impairment. Therefore, the initial therapeutic approach must be vigorous in all children.
ISSN:1738-1061
2092-7258
2713-4148
DOI:10.3345/kjp.2010.53.11.936