A case of acute disseminated encephalomyelitis associated with hepatitis C virus infection

Acute disseminated encephalomyelitis (ADEM) is a monophasic autoimmune demyelinating disease of the central nervous system, which typically follows acute viral or bacterial infection or vaccination. We report a case of ADEM associated with hepatitis C virus (HCV) infection with positive serum and ce...

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Bibliographic Details
Published in:Yonsei medical journal 2012, 53(4), , pp.856-858
Main Authors: Sim, Jae Eun, Lee, Jun-Bum, Cho, Yu Na, Suh, Sang Hyun, Kim, Ja Kyung, Lee, Kyung-Yul
Format: Article
Language:English
Subjects:
Case Report
Encephalomyelitis, Acute Disseminated - diagnosis
Encephalomyelitis, Acute Disseminated - drug therapy
Encephalomyelitis, Acute Disseminated - etiology
Encephalomyelitis, Acute Disseminated - virology
Female
Hepacivirus - pathogenicity
Hepatitis C - complications
Humans
Methylprednisolone - therapeutic use
Middle Aged
의학일반
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Description
Summary:Acute disseminated encephalomyelitis (ADEM) is a monophasic autoimmune demyelinating disease of the central nervous system, which typically follows acute viral or bacterial infection or vaccination. We report a case of ADEM associated with hepatitis C virus (HCV) infection with positive serum and cerebrospinal fluid (CSF) anti-HCV antibody. After steroid treatment, neurologic symptoms were improved. Virus triggers autoimmunity or direct viral invasion plays a part in the genesis of ADEM. This is the first reported case of ADEM with anti-HCV antibody in the CSF.
ISSN:0513-5796
1976-2437
DOI:10.3349/ymj.2012.53.4.856