Effects of multiple drilling on the ischemic capital femoral epiphysis of immature piglets

This study investigated the effects of multiple drilling on the immature capital femoral epiphysis following ischemic injury in a piglet model. Ischemic necrosis of capital femoral epiphysis was induced bilaterally in 12 piglets using a cervical ligation method. Three weeks later, medial, central, a...

Full description

Saved in:
Bibliographic Details
Published in:Yonsei medical journal 2011, 52(5), , pp.809-817
Main Authors: Kong, Sun Young, Gong, Sun Young, Kim, Hyun Woo, Park, Hui-Wan, Lee, Seung Yup, Lee, Ki Seok
Format: Article
Language:English
Subjects:
Animals
Bone Remodeling
Disease Models, Animal
Epiphyses - blood supply
Epiphyses - pathology
Epiphyses - surgery
Female
Femur Head - blood supply
Femur Head - pathology
Femur Head - surgery
Humans
Ischemia - pathology
Ischemia - surgery
Legg-Calve-Perthes Disease - pathology
Legg-Calve-Perthes Disease - surgery
Original
Swine
의학일반
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:This study investigated the effects of multiple drilling on the immature capital femoral epiphysis following ischemic injury in a piglet model. Ischemic necrosis of capital femoral epiphysis was induced bilaterally in 12 piglets using a cervical ligation method. Three weeks later, medial, central, and lateral 3 drill holes were made on the left femoral head using 0.062" K-wire. At 3, 6, 9, and 12 weeks following the multiple drilling, femoral heads were harvested from each three piglets. On histologic examination, percent of revascularization, percent of osteoblast surface, capital femoral epiphyseal quotient and proximal femoral growth plate height were evaluated. Untreated right femoral heads served as control. While percent of revascularization of left capital femoral epiphysis with multiple drilling was significantly higher than untreated control side (p
ISSN:0513-5796
1976-2437
DOI:10.3349/ymj.2011.52.5.809