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A case of type B lactic acidosis in acute leukemia

Type B lactic acidosis is a rare condition in patients with solid tumors or hematological malignancies. Although there have been several theories to explain its mechanism, the exact cause of lactic acidosis remains to be discovered. Lactic acidosis is usually related to increased tumor burden in pat...

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Bibliographic Details
Published in:Yonsei medical journal 2010, 51(3), , pp.460-462
Main Authors: Lee, Hae Seung, Kim, Hyun Jung, Choi, Soojeong, Kim, Chan Kyu, Lee, Nam Su, Lee, Kyu Taek, Won, Jong Ho, Park, Hee Sook, Hong, Dae Sik
Format: Article
Language:English
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Summary:Type B lactic acidosis is a rare condition in patients with solid tumors or hematological malignancies. Although there have been several theories to explain its mechanism, the exact cause of lactic acidosis remains to be discovered. Lactic acidosis is usually related to increased tumor burden in patients with malignancy. We experienced a case of lactic acidosis in a 39-year-old man who visited an emergency room because of dyspnea, and the cause of lactic acidosis turned out to be recurrent acute leukemia. Chemotherapy relieved the degree of lactic acidosis initially, but as the disease progressed, lactic acidosis became aggravated. Type B lactic acidosis can be a clinical presentation of acute exacerbation of acute leukemia.
ISSN:0513-5796
1976-2437
DOI:10.3349/ymj.2010.51.3.460