Thrombosuction utilizing an export aspiration catheter during primary percutaneous coronary intervention in acute myocardial infarction

Effective myocardial reperfusion after primary PCI for an AMI in lesions with a thrombus is limited by distal embolization and the slow/no reflow phenomenon. We evaluated the efficacy of a thrombus reduction technique using an export aspiration catheter for thrombosuction during primary PCI. We anal...

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Bibliographic Details
Published in:Yonsei medical journal 2007, 48(2), , pp.261-269
Main Authors: Kang, Woong Chol, Ahn, Tae Hoon, Han, Seung Hwan, Chung, Wook-Jin, Shin, Mi Seung, Koh, Kwang Kon, Choi, In Suck, Shin, Eak Kyun
Format: Article
Language:English
Subjects:
Aged
Angioplasty, Balloon, Coronary - instrumentation
Angioplasty, Balloon, Coronary - methods
Catheterization - instrumentation
Catheterization - methods
Coronary Disease - epidemiology
Humans
Male
Middle Aged
Myocardial Infarction - therapy
Original
Suction - instrumentation
Suction - methods
Treatment Outcome
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Summary:Effective myocardial reperfusion after primary PCI for an AMI in lesions with a thrombus is limited by distal embolization and the slow/no reflow phenomenon. We evaluated the efficacy of a thrombus reduction technique using an export aspiration catheter for thrombosuction during primary PCI. We analyzed 62 patients with AMIs who underwent primary PCI and had a thrombi burden during thrombosuction using an EAC (EAC group; n=31) or without thrombosuction (control group; n=31). Thrombosuction with an EAC was performed safely in all the patients in EAC group without any complications. After the PCI, restoration to a TIMI flow grade 3 was significantly more frequent in the EAC group (26/31 vs. 20/31, p < 0.05). However, the TIMI perfusion grade did not differ between the two groups. Further, the corrected TIMI frame counts were lower in the EAC group (23.9 +/- 15.1 vs. 34.8 +/- 22.5, p < 0.05). Although there was no statistical significance, a greater incidence of distal embolization was observed in the control group (16.1%, 5/31) as compared to the EAC group (0/31) (p= 0.056). However, the incidence of major adverse cardiac events at 1 and 6 months did not differ between the two groups. For AMIs, thrombosuction with an EAC before or during PCI is a safe and potentially effective method for restoration of the coronary flow.
ISSN:0513-5796
1976-2437
DOI:10.3349/ymj.2007.48.2.261