Contrast-Enhanced Endoscopic Ultrasound for Differentially Diagnosing Autoimmune Pancreatitis and Pancreatic Cancer

• Published in: Gut and liver 2018, 12(5), , pp.591-596
• Main Authors: Cho, Min Keun, Moon, Sung-Hoon, Song, Tae Jun, Kim, Raymond E, Oh, Dong Wook, Park, Do Hyun, Lee, Sang Soo, Seo, Dong Wan, Lee, Sung Koo, Kim, Myung-Hwan
• Format: Article
• Language: English
• Subjects: Adult; Aged; Aged, 80 and over; Autoimmune Diseases - diagnostic imaging; autoimmune pancreatitis; biopsy; Contrast Media; Diagnosis, Differential; endosonography; Endosonography - methods; Endosonography - statistics & numerical data; Female; fine-needle; Humans; Male; Middle Aged; Original; Pancreas - diagnostic imaging; pancreatic neoplasms; Pancreatic Neoplasms - diagnostic imaging; Pancreatitis - diagnostic imaging; Prospective Studies; Sensitivity and Specificity; 내과학
• ISSN: 1976-2283; 2005-1212
• DOI: 10.5009/gnl17391

Differentially diagnosing focal-type autoimmune pancreatitis (f-AIP) and pancreatic cancer (PC) is challenging. Contrast-enhanced harmonic endoscopic ultrasound (CEH-EUS) may provide information for differentiating pancreatic masses. In this study, we evaluated the usefulness of CEH-EUS in differentiating f-AIP from PC. Data were collected prospectively and analyzed on patients who underwent CEH-EUS between May 2014 and May 2015. Eighty consecutive patients were diagnosed with f-AIP or PC. PC and f-AIP were compared for enhancement intensity, contrast agent distribution, and internal vasculature. The study group comprised 53 PC patients and 27 f-AIP patients (17 with type-1 AIP [15 definite and two probable], two with probable type-2 AIP, and eight with AIP, not otherwise specified). Hyper- to iso-enhancement in the arterial phase (f-AIP, 89% vs PC, 13%; p