Etiology of hepatocellular carcinoma and treatment through medicinal plants: a comprehensive review

• Published in: Advances in traditional medicine (Online) 2018, 18(3), , pp.187-197
• Main Authors: Sundas Nasreen, Sobia Safeer, Kamaran Khurshid Dar, Saiqa Andleeb, Mubashir Ejaz, Muhammad Adeeb Khan, Shaukat Ali
• Format: Article
• Language: English
• Subjects: 한의학
• ISSN: 2662-4052; 2662-4060
• DOI: 10.1007/s13596-018-0330-1

Liver is a power house of the body for many components such as vitamins, minerals, iron and glycogen and play role in biotransformation. Some ingredients of our diet (foodstuff s may contain with afl atoxin B1, vinyl chloride, tobacco, heavy alcohol intake, fried meat, coff ee and oral contraceptives),when metabolized become tremendous for liver and leads toward hepatocellular carcinoma (HCC). HCC occurs through cyclical liver injury due to infl ammation and DNA damaging as a result of oxidative stress. Phytochemicals of medicinal plants have curative potential against liver cancer due to presence of linalool, eucalyptol, borneol, thujone, camphor, 4-terpineol, monoterpenes and α -cadinol, sophytotherapies have several advantages over conventional chemotherapies. According to literature survey Acanthus ilicifolius, Allium sativum, Artemisiaprinceps, Artemisia vulgaris, Amorphophallus campanulatus, Brucea javanica, Broussonetia luzonica, Dracocephalum kotschyi, Graptopetalum paraguayense, Nigella sativa, Petasites japonicas, Silybum marianum, Bergenia ciliata , Cassia fi stula and Picrorhiza scrophularilora have vital bioactive compounds used against hepatocellular carcinoma. KCI Citation Count: 0