Complete Versus Culprit-Only Revascularization for ST-Segment Elevation Myocardial Infarction and Multivessel Disease in the 2nd Generation Drug-Eluting Stent Era: Data from the INTERSTELLAR Registry

• Published in: Korean circulation journal 2018, 48(11), , pp.989-999
• Main Authors: Kwon, Sung Woo, Park, Sang Don, Moon, Jeonggeun, Oh, Pyung Chun, Jang, Ho Jun, Park, Hyun Woo, Kim, Tae Hoon, Lee, Kyounghoon, Suh, Jon, Kang, WoongChol
• Format: Article
• Language: English
• Subjects: Original; 내과학
• ISSN: 1738-5520; 1738-5555
• DOI: 10.4070/kcj.2017.0387

BACKGROUND AND OBJECTIVESWe aimed to compare outcomes of complete revascularization (CR) versus culprit-only revascularization for ST-segment elevation myocardial infarction (STEMI) and multivessel disease (MVD) in the 2nd generation drug-eluting stent (DES) era. METHODSFrom 2009 to 2014, patients with STEMI and MVD, who underwent primary percutaneous coronary intervention (PCI) using a 2nd generation DES for culprit lesions were enrolled. CR was defined as PCI for a non-infarct-related artery during the index admission. Major adverse cardiovascular event (MACE) was defined as cardiovascular (CV) death, non-fatal myocardial infarction, target lesion revascularization, or heart failure during the follow-up year. RESULTSIn total, 705 MVD patients were suitable for the analysis, of whom 286 (41%) underwent culprit-only PCI and 419 (59%) underwent CR during the index admission. The incidence of MACE was 11.5% in the CR group versus 18.5% in the culprit-only group (hazard ratio [HR], 0.56; 95% confidence interval [CI], 0.37-0.86; p