Changes in the Thyroid Hormone Profiles in Children with Nephrotic Syndrome

We compared thyroid hormone profiles in children with nephrotic syndrome (NS) at nephrotic phase and after remission. This study included thirty-one pediatric NS patients. Thyroid hormone profiles consist of serum T3, T4, TSH and free T4. Of the 31 patients, 16 (51.6%) showed abnormal findings in th...

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Bibliographic Details
Published in:Clinical and experimental pediatrics 2019, 62(3), , pp.85-89
Main Authors: Jung, Sun Hee, Lee, Jeong Eun, Chung, Woo Yeong
Format: Article
Language:English
Subjects:
Antibodies
Biopsy
Child
Hormones
Hypothyroidism
Kidney diseases
Nephrotic syndrome
Original
Patients
Pediatrics
Proteins
Steroids
Thyroid gland
Thyroid hormones
Urine
소아과학
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Summary:We compared thyroid hormone profiles in children with nephrotic syndrome (NS) at nephrotic phase and after remission. This study included thirty-one pediatric NS patients. Thyroid hormone profiles consist of serum T3, T4, TSH and free T4. Of the 31 patients, 16 (51.6%) showed abnormal findings in their thyroid hormone profiles: six, overt hypothyroidism; eight, subclinical hypothyroidism, and two, low T3 syndrome. The mean serum T3, T4, and free T4 levels were 82.37±23.64 ng/dL and 117.88±29.49 ng/dl, 5.47±1.14 µg/dl and 7.91±1.56 µg/dl, and 1.02±0.26 ng/dl and 1.38±0.23 ng/dl at NS nephrotic phase and remission, respectively, and were significantly lower at NS nephrotic phase (P=0.0007,
ISSN:1738-1061
2092-7258
2713-4148
DOI:10.3345/kjp.2018.06891