Nanomaterial-modified Hybrid Platforms for Precise Electrochemical Detection of Dopamine

Dopamine belongs to the class of catecholamine neurotransmitters which have vital roles in the human central nervous system. Due to its importance in signal transmission in the nervous system, the abnormal release of dopamine is critical for the development of a number of neurological diseases/disor...

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Bibliographic Details
Published in:Biochip journal 2019, 13(1), , pp.20-29
Main Authors: Suhito, Intan Rosalina, Angeline, Novi, Kim, Tae-Hyung
Format: Article
Language:English
Subjects:
Attention deficit hyperactivity disorder
Biomedical Engineering and Bioengineering
Biosensors
Biotechnology
Catecholamine
Catecholamines
Central nervous system
Chemical sensors
Chemistry
Composite materials
Dopamine
Drug addiction
Electrochemical analysis
Electrodes
Electrons
Glucose
Gold
Graphene
Methods
Nanomaterials
Nanoparticles
Nanotechnology
Neurological diseases
Neurological disorders
Neurotransmitters
Platforms
Review Article
Sensitivity enhancement
Signal transmission
Transition metal compounds
Uric acid
Voltammetry
생물공학
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Summary:Dopamine belongs to the class of catecholamine neurotransmitters which have vital roles in the human central nervous system. Due to its importance in signal transmission in the nervous system, the abnormal release of dopamine is critical for the development of a number of neurological diseases/disorders, including Parkinson’s diseases, attention deficit hyperactivity disorder, and even drug addiction. Hence, there is an utmost need to develop platforms for the quantitative detection of dopamine in the human body in a rapid, sensitive, and label-free manner. A variety of nanomaterials have been explored and integrated into dopamine sensing platforms; in particular, electrochemical sensors can enhance both the sensitivity and selectivity toward dopamine, with promising results. The aim of this review is to summarize recent research on nanomaterial-modified dopamine electrochemical sensor platforms, particularly those that use nanoparticle-, graphene composite-, and transition metal dichalcogenide-modified electrodes. The information presented in this review might motivate the discovery or extension of nanomaterials with beneficial properties for the development of biosensors to detect various neurotransmitters including dopamine.
ISSN:1976-0280
2092-7843
DOI:10.1007/s13206-019-3106-x