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Changes in Serotype of Streptococcus pneumoniae After the Introduction of the 13-Valent Pneumococcal Vaccine in a Homogenous Population on Jeju Island

We compared the serotypes of between the pre-pneumococcal conjugate vaccine (PCV)13 era and post-PCV13 era among homogenous inhabitants of an isolated South Korean island. A total of 325 strains were isolated. In the pre-PCV13 era, 19A/F, 15A/F, 19B, and 23A serotypes were identified. In the post-PC...

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Bibliographic Details
Published in:Infection & chemotherapy 2019, 51(1), , pp.67-72
Main Authors: Yoo, Jeong Rae, Heo, Sang Taek, Oh, Hyunjoo, Oh, Suhyun, Kim, Young Ree, Lee, Keun Hwa
Format: Article
Language:English
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Summary:We compared the serotypes of between the pre-pneumococcal conjugate vaccine (PCV)13 era and post-PCV13 era among homogenous inhabitants of an isolated South Korean island. A total of 325 strains were isolated. In the pre-PCV13 era, 19A/F, 15A/F, 19B, and 23A serotypes were identified. In the post-PCV13 era, 15 serotypes were identified. The 19F and 23A serotypes showed the highest prevalence in the pre- and post-PCV13 era, respectively. After PCV13 introduction, the PCV 13 serotype coverage rate was decreased (80.0% and 30.5% in the pre- and post-PCV13 eras, respectively), while the proportion of non-PCV 13 serotypes increased.
ISSN:2093-2340
2092-6448
DOI:10.3947/ic.2019.51.1.67