Impact of triple-negative breast cancer phenotype on prognosis in patients with stage I breast cancer

Although most patients with stage I breast cancer have a good prognosis, their clinical outcomes may vary significantly. We assessed clinical outcomes and prognostic factors in stage I breast cancer patients with and without triple-negative breast cancer (TNBC) phenotype. Of 2,489 patients undergoin...

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Bibliographic Details
Published in:Journal of breast cancer 2012, 15(2), 60, pp.197-202
Main Authors: Kim, Jeong Eun, Ahn, Heui June, Ahn, Jin-Hee, Yoon, Dok Hyun, Kim, Sung-Bae, Jung, Kyung Hae, Gong, Gyung-Yub, Kim, Mi-Jung, Son, Byung Ho, Ahn, Sei Hyun
Format: Article
Language:English
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일반외과학
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Summary:Although most patients with stage I breast cancer have a good prognosis, their clinical outcomes may vary significantly. We assessed clinical outcomes and prognostic factors in stage I breast cancer patients with and without triple-negative breast cancer (TNBC) phenotype. Of 2,489 patients undergoing breast cancer surgery between January 1998 and December 2002, 554 (22.3%) had stage I breast cancer (tumor size ≤2 cm, and lymph node-negative). TNBC was defined as a primary tumor negative for estrogen and progesterone receptors (Allred scores 1 cm (87.2% vs. 75.8%, p=0.028) and received adjuvant chemotherapy (79.5% vs. 44.7%, p
ISSN:1738-6756
2092-9900
DOI:10.4048/jbc.2012.15.2.197