Electrospun Polycaprolactone/Graphene/Baghdadite Composite Nanofibres with Improved Mechanical and Biological Properties

Polycaprolactone (PCL) based nanocomposite scaffolds containing graphene (Gr) and baghdadite (BAG) nanoparticles were fabricated using the electrospinning method. Mechanical properties of the scaffolds were evaluated. Viability and adhesion of cells on the scaffolds were confirmed using fluorescence...

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Bibliographic Details
Published in:Fibers and polymers 2019, 20(5), , pp.982-990
Main Authors: Samani, Delara Aarabi, Doostmohammadi, Ali, Nilforoushan, Mohammad Reza, Nazari, Hassan
Format: Article
Language:English
Subjects:
Adhesion tests
Biological properties
Cell adhesion
Cell adhesion & migration
Chemistry
Chemistry and Materials Science
Fluorescence
Graphene
Mechanical properties
Nanocomposites
Nanofibers
Nanoparticles
Optical microscopy
Polycaprolactone
Polymer Sciences
Scaffolds
Viability
섬유공학
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Summary:Polycaprolactone (PCL) based nanocomposite scaffolds containing graphene (Gr) and baghdadite (BAG) nanoparticles were fabricated using the electrospinning method. Mechanical properties of the scaffolds were evaluated. Viability and adhesion of cells on the scaffolds were confirmed using fluorescence optical microscopy, MTT and FE-SEM analysis methods. The results indicated that incorporation of various concentrations of BAG from 1 to 3 wt% notably improved the mechanical properties. Cell adhesion assay revealed that the addition of BAG nanoparticles to PCL-Gr scaffold caused further adhesion, viability, and proliferation of the cells.
ISSN:1229-9197
1875-0052
DOI:10.1007/s12221-019-1161-5