Association of Nutritional Status with Cognitive Stage in the Elderly Korean Population: The Korean Brain Aging Study for the Early Diagnosis and Prediction of Alzheimer's Disease

• Published in: Journal of clinical neurology (Seoul, Korea) 2019, 15(3), , pp.292-300
• Main Authors: Jang, Jae Won, Kim, Yeshin, Choi, Yong Ho, Lee, Jong Min, Yoon, Bora, Park, Kyung Won, Kim, Si Eun, Kim, Hee Jin, Yoon, Soo Jin, Jeong, Jee Hyang, Kim, Eun Joo, Jung, Na Yeon, Hwang, Jihye, Kang, Ju Hee, Hong, Jin Yong, Choi, Seong Hye
• Format: Article
• Language: English
• Subjects: Original; 신경과학
• ISSN: 1738-6586; 2005-5013
• DOI: 10.3988/jcn.2019.15.3.292

Epidemiological studies have suggested the presence of strong correlations among diet, lifestyle, and dementia onset. However, these studies have unfortunately had major limitations due to their inability to fully control the various potential confounders affecting the nutritional status. The purpose of the current study was to determine the nutritional status of participants in the Korean Brain Aging Study for the Early Diagnosis and Prediction of Alzheimer's Disease (KBASE) and to identify clinical risk factors for being at risk of malnutrition or being malnourished. Baseline data from 212 participants [119 cognitively unimpaired (CU), 56 with mild cognitive impairment (MCI), and 37 with dementia] included in the KBASE database were analyzed. All participants underwent a comprehensive cognitive test and MRI at baseline. The presence of malnutrition at baseline was measured by the Mini Nutritional Assessment score. We examined the cross-sectional relationships of clinical findings with nutritional status using multiple logistic regression applied to variables for which