Methylenetetrahydrofolate reductase 677 genotype-specific reference values for plasma homocysteine and serum folate concentrations in korean population aged 45 to 74 years: the Namwon study

The reference interval for plasma total homocysteine (tHcy) and serum folate concentrations were estimated. Total of 3,154 reference individuals (1,029 men and 2,125 women) were selected based on stringent exclusion criteria. For plasma tHcy concentration (µM/L), reference values (median [5-95 perce...

Full description

Saved in:
Bibliographic Details
Published in:Journal of Korean medical science 2014, 29(5), 188, pp.743-747
Main Authors: Kweon, Sun-Seog, Lee, Young-Hoon, Jeong, Seul-Ki, Nam, Hae-Sung, Park, Kyeong-Soo, Choi, Seong-Woo, Kim, Bok-Hee, Kim, Hee Nam, Choi, Jin-Su, Shin, Min-Ho
Format: Article
Language:English
Subjects:
Age Factors
Aged
Aging
Brief Communication
Cohort Studies
Female
Folic Acid - blood
Genotype
Homocysteine - blood
Humans
Male
Methylenetetrahydrofolate Reductase (NADPH2) - genetics
Middle Aged
Reference Values
Republic of Korea
Sex Factors
의학일반
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The reference interval for plasma total homocysteine (tHcy) and serum folate concentrations were estimated. Total of 3,154 reference individuals (1,029 men and 2,125 women) were selected based on stringent exclusion criteria. For plasma tHcy concentration (µM/L), reference values (median [5-95 percentile]) were 7.72 (5.03 to 13.80) and 6.09 (3.95-10.19) in men and women, respectively. For serum folate concentration (nM/L), reference values were 23.71 (11.73-38.44) and 28.95 (15.23-40.44) in men and women, respectively. The tHcy levels of both genders in the present study were lower than those in previous reports from other countries and Korea.
ISSN:1011-8934
1598-6357
DOI:10.3346/jkms.2014.29.5.743