Human papillomavirus prevalence and genotype distribution among HIV-infected women in Korea

• Published in: Journal of Korean medical science 2014, 29(1), 184, pp.32-37
• Main Authors: Park, Eun Kyoung, Cho, Heerim, Lee, Sun Hee, Lee, Seung Geun, Lee, Sang Yeup, Kim, Ki Hyung, Lee, Chang Hun, Chung, Joo Seop, Kwak, Ihm Soo
• Format: Article
• Language: English
• Subjects: Adult; Age Factors; Cervix Uteri - virology; DNA Probes, HPV; DNA, Viral - genetics; Female; Genotype; HIV Infections - complications; HIV Infections - epidemiology; HIV Infections - genetics; HIV-1 - genetics; Human papillomavirus 11 - genetics; Human papillomavirus 11 - isolation & purification; Human papillomavirus 16 - genetics; Human papillomavirus 16 - isolation & purification; Human papillomavirus 18 - genetics; Human papillomavirus 18 - isolation & purification; Human papillomavirus 6 - genetics; Human papillomavirus 6 - isolation & purification; Humans; Middle Aged; Original; Papillomavirus Infections - complications; Papillomavirus Infections - epidemiology; Papillomavirus Infections - genetics; Prevalence; Republic of Korea - epidemiology; Retrospective Studies; Risk Factors; Uterine Cervical Neoplasms - epidemiology; Uterine Cervical Neoplasms - genetics; Uterine Cervical Neoplasms - virology; 의학일반
• ISSN: 1011-8934; 1598-6357
• DOI: 10.3346/jkms.2014.29.1.32

The epidemiology on human papillomavirus (HPV) among human immunodeficiency virus (HIV)-infected women in Korea is not well established. A retrospective study was conducted to determine the prevalence and genotype distribution of HPV infection among HIV-infected women in Korea. HPV DNA genotype and cervical cytology were examined in 60 HIV-positive women and 1,938 HIV-negative women. HPV genotypes were analyzed by using a HPV DNA chip. HIV-infected women had higher prevalence of high-risk HPV (hr-HPV) infection (30% vs 4.9%, adjusted odds ratio [AOR], 6.96; 95% confidence interval [CI], 3.63-13.34, P