Prevalence and risk factors of early-stage age-related macular degeneration in patients examined at a health promotion center in Korea

We evaluated the prevalence and risk factors for early age-related macular degeneration (AMD) in Koreans 50 yr of age or older who were examined at a single health promotion center. We retrospectively reviewed the records of 10,449 subjects who visited the center over a 6-month period. Fundus photog...

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Bibliographic Details
Published in:Journal of Korean medical science 2012, 27(5), 163, pp.537-541
Main Authors: Moon, Byung Gil, Joe, Soo Geun, Hwang, Jong-uk, Kim, Hong Kyu, Choe, Jaewon, Yoon, Young Hee
Format: Article
Language:English
Subjects:
Age Factors
Cohort Studies
Community Health Centers
Female
Humans
Hyperlipidemias - complications
Macular Degeneration - complications
Macular Degeneration - diagnosis
Macular Degeneration - epidemiology
Male
Middle Aged
Odds Ratio
Original
Prevalence
Republic of Korea - epidemiology
Retrospective Studies
Risk Factors
Sex Factors
Smoking
Surveys and Questionnaires
의학일반
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Summary:We evaluated the prevalence and risk factors for early age-related macular degeneration (AMD) in Koreans 50 yr of age or older who were examined at a single health promotion center. We retrospectively reviewed the records of 10,449 subjects who visited the center over a 6-month period. Fundus photography was performed on all subjects, and systematic risk factor analysis was conducted using a structured questionnaire. All patients (n = 322) were initially diagnosed with drusen or early AMD using fundoscopy; the control group (n = 10,127) were those yielding normal fundoscopy findings. The age- and gender-adjusted prevalence of early AMD was 3.08%. Advanced age, male gender, smoking status, hyperlipidemia, working outdoors, and residence in rural areas were all significantly associated with an increased risk for development of early AMD. Higher-level ingestion of fruit or herbal medication and an increased amount of exercise were associated with a lower risk of early AMD development. In our Korean cohort, consisting principally of relatively healthy, middle-class urban adults, the prevalence of early AMD was 3.08% that is similar to that reported in earlier epidemiological studies. Several modifiable risk factors such as smoking and hyperlipidemia are associated with the prevalence of early AMD in our cohort.
ISSN:1011-8934
1598-6357
DOI:10.3346/jkms.2012.27.5.537