Comparison of clinical efficacy between a single administration of long-acting gonadotrophin-releasing hormone agonist (GnRHa) and daily administrations of short-acting GnRHa in in vitro fertilization-embryo transfer cycles

This study was aimed to evaluate the efficacy of a single administration of long-acting gonadotrophin-releasing hormone agonist (GnRHa) as compared with daily administrations of short-acting GnRHa in controlled ovarian hyperstimulation (COH) for in vitro fertilization and embryo transfer (IVF-ET) cy...

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Bibliographic Details
Published in:Journal of Korean medical science 2008, 23(4), , pp.662-666
Main Authors: Cheon, Kang Woo, Song, Sang Jin, Choi, Bum Chae, Lee, Seung Chul, Lee, Hong Bok, Yu, Seung Youn, Yoo, Keun Jai
Format: Article
Language:English
Subjects:
Adult
Buserelin - therapeutic use
Embryo Transfer
Female
Fertilization in Vitro
Follicle Stimulating Hormone - therapeutic use
Goserelin - therapeutic use
Humans
Leuprolide - therapeutic use
Original
의학일반
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Summary:This study was aimed to evaluate the efficacy of a single administration of long-acting gonadotrophin-releasing hormone agonist (GnRHa) as compared with daily administrations of short-acting GnRHa in controlled ovarian hyperstimulation (COH) for in vitro fertilization and embryo transfer (IVF-ET) cycles. The mean dosage of recombinant follicle-stimulating hormone (rFSH) required for COH (2,354.5+/-244.2 vs. 2,012.5+/-626.1 IU) and the rFSH dosage per retrieved oocyte (336.7+/-230.4 vs. 292.1+/-540.4 IU) were significantly higher in the long-acting GnRHa group (N= 22) than those in the short-acting GnRHa group (N=28) (p
ISSN:1011-8934
1598-6357
DOI:10.3346/jkms.2008.23.4.662