Treatment of Hidradenitis Suppurativa Patient with Klinefelter Syndrome by Adalimumab

Hidradenitis suppurativa (HS) is a chronic, inflammatory and painful skin disease with recurrent nodules and tracts involving the intertriginous regions. It is known that the patient with HS shows an increased risk of metabolic disorders such as diabetes, metabolic syndrome and autoimmune diseases....

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Bibliographic Details
Published in:Annals of dermatology 2019, 31(4), , pp.446-449
Main Authors: Shin, Ji Yeoun, Hong, Jung Yeon, Lee, Ho Jung, Sim, Chang Yoon, Park, Young Lip, Lee, Jong Suk, Lee, Sung Yul, Kim, Jung Eun
Format: Article
Language:English
Subjects:
Case Report
피부과학
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Summary:Hidradenitis suppurativa (HS) is a chronic, inflammatory and painful skin disease with recurrent nodules and tracts involving the intertriginous regions. It is known that the patient with HS shows an increased risk of metabolic disorders such as diabetes, metabolic syndrome and autoimmune diseases. Klinefelter syndrome (KS) is a sex chromosomal disorder occurring in males due to an abnormality of sexual differentiation, characterized by 47, XXY karyotype. Also, KS is related with somatic comorbidities such as metabolic syndrome, autoimmune and rheumatologic disorders as HS is. We report a HS patient with KS who shows a big improvement while on tumor necrosis factor-alpha inhibitor treatment.
ISSN:1013-9087
2005-3894
DOI:10.5021/ad.2019.31.4.446