Preoperative Risk Factors for Pathologic N2 Metastasis in Positron Emission Tomography-Computed Tomography-Diagnosed N0-1 Non-Small Cell Lung Cancer

Accurate mediastinal lymph node staging is vital for the optimal therapy and prognostication of patients with lung cancer. This study aimed to determine the preoperative risk factors for pN2 disease, as well as its incidence and long-term outcomes, in patients with clinical N0-1 non-small cell lung...

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Bibliographic Details
Published in:Journal of chest surgery 2019, 52(4), , pp.221-226
Main Authors: Yoon, Tae-Hong, Lee, Chul-Ho, Park, Ki-Sung, Bae, Chi-Hoon, Cho, Jun-Woo, Jang, Jae-Seok
Format: Article
Language:English
Subjects:
Clinical Research
Computed tomography
Lymph nodes
Neoplasm metastasis
Non-small-cell lung carcinoma
Positron emission tomography
흉부외과학
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Summary:Accurate mediastinal lymph node staging is vital for the optimal therapy and prognostication of patients with lung cancer. This study aimed to determine the preoperative risk factors for pN2 disease, as well as its incidence and long-term outcomes, in patients with clinical N0-1 non-small cell lung cancer. We retrospectively analyzed patients who were treated surgically for primary non-small cell lung cancer from November 2005 to December 2014. Patients staged as clinical N0-1 via chest computed tomography (CT) and positron emission tomography (PET)-CT were divided into two groups (pN0-1 and pN2) and compared. In a univariate analysis, the significant preoperative risk factors for pN2 included a large tumor size (p=0.083), high maximum standard uptake value on PET (p
ISSN:2233-601X
2765-1606
2093-6516
2765-1614
DOI:10.5090/kjtcs.2019.52.4.221