Bioengineered Short Carbon Nanotubes as Tumor-Targeted Carriers for Biomedical Imaging

Cancer is one of the leading causes of death in human beings. Therefore, it is important to detect specific target tumors earlier enough in the formative stages of cancer without causing negative side effects and damages to the body. In this study, we proposed bio-engineered short mussel adhesive pr...

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Bibliographic Details
Published in:Macromolecular research 2019, 27(8), , pp.833-838
Main Authors: Park, Sunho, Kim, Teayeop, Jo, Danbi, Jung, Jin Seok, Jo, Gayoung, Park, Yunjeong, Kang, Eun Sung, Kim, Yong Ho, Kim, Jangho, Kim, Kyunghoon, Hyun, Hoon
Format: Article
Language:English
Subjects:
Bioengineering
Cancer
Carbon nanotubes
Characterization and Evaluation of Materials
Chemistry
Chemistry and Materials Science
Complex Fluids and Microfluidics
Infrared imaging
Medical imaging
Nanochemistry
Nanotechnology
Physical Chemistry
Polymer Sciences
Side effects
Soft and Granular Matter
Target detection
Tumors
고분자공학
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Summary:Cancer is one of the leading causes of death in human beings. Therefore, it is important to detect specific target tumors earlier enough in the formative stages of cancer without causing negative side effects and damages to the body. In this study, we proposed bio-engineered short mussel adhesive proteins (MAPs)-carbon nanotubes (CNTs) as specific tumor-targeted carriers for biomedical imaging. Short CNT near-infrared fluorophore (NIRF) hybrid carriers that were developed accumulated in the tumors with exceptional clearance and specific targeting in less time, and these results indicated that bioengineered short CNT-based carriers have great potential for real time tumor imaging.
ISSN:1598-5032
2092-7673
DOI:10.1007/s13233-019-7141-1