The effects of coenzyme Q10 supplement on blood lipid indices and hepatic antioxidant defense system in SD rats fed a high cholesterol diet

A total of 24 SD rats were allotted to four treatment groups such as the control (CON), 1% of cholesterol diet (CHO), 0.5% of coenzyme Q10 (COQ) and 1% of cholesterol plus 0.5% of coenzyme Q10 (CHCQ) groups to determine the effects of coenzyme Q10 (CoQ10) on the antioxidant defense system in rats. T...

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Bibliographic Details
Published in:Laboratory animal research 2019, 35(2), , pp.86-93
Main Authors: Kim, Ha-Na, Jeon, Dong-Gyung, Lim, Yong, Jang, In-Surk
Format: Article
Language:English
Subjects:
Animals
Antioxidant enzymes
Antioxidants
Blood
Body weight
Body weight gain
Cardiovascular disease
Cholesterol
Coenzyme Q10
Diet
Dietary supplements
Enzymes
Gene expression
Glutathione peroxidase
Glutathione transferase
High cholesterol diet
High density lipoprotein
Lipid indices
Lipid peroxidation
Lipids
Liver
Metabolism
Oxidative stress
Physiology
Sucrose
Superoxide dismutase
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Summary:A total of 24 SD rats were allotted to four treatment groups such as the control (CON), 1% of cholesterol diet (CHO), 0.5% of coenzyme Q10 (COQ) and 1% of cholesterol plus 0.5% of coenzyme Q10 (CHCQ) groups to determine the effects of coenzyme Q10 (CoQ10) on the antioxidant defense system in rats. The body weight, weight gain, liver weight and abdominal fat pads were unaffected by 0.5% of CoQ10 supplement in the rats. The level of triglyceride and HDL-cholesterol levels in the blood was significantly increased (p
ISSN:2233-7660
1738-6055
2233-7660
DOI:10.1186/s42826-019-0013-1